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种植体植入术后感染:与失败风险增加相关的变量。

Postoperative infections after dental implant placement: Variables associated with increased risk of failure.

机构信息

Oral Surgery and Implantology, Faculty of Medicine and Health Sciences, University of Barcelona, Barcelona, Spain.

Oral Surgery and Implantology, Faculty of Medicine, Efhre International University, Belize City, Belize.

出版信息

J Periodontol. 2018 Oct;89(10):1165-1173. doi: 10.1002/JPER.18-0024. Epub 2018 Sep 2.

Abstract

BACKGROUND

Wound infections after dental implant placement are a rare finding that might lead to early implant failure. However, the available information on this topic is scarce.

METHODS

This retrospective cohort study was conducted to determine factors that may increase the failure rate of dental implants that presented a postoperative infection during the osseointegration period. Postoperative infections were defined as the presence of pus or fistula in the surgical area, with pain or tenderness, swelling, redness, and heat or fever, before prosthetic loading. A bivariate and multivariate analysis of the data using Cox proportional-hazards regression was performed to detect prognostic factors for implant failure in patients that suffer infections.

RESULTS

The patient-based prevalence of postoperative infections after implant placement was 2.80% (95% confidence interval (95%CI): 2.04% to 3.83%). Thirty-three out of 37 (89.19%) patients with infections had to be surgically retreated because of antibiotic failure and 65% of the infected implants were removed. The bivariate analysis showed a significant association between implant failure and the collar surface (HR: 3.12; 95% CI: 1.16 to 8.41; P = 0.014). Cox proportional-hazards regression indicated that rough-surfaced collars increased 2.35 times the likelihood of failure (95% CI: 0.87 to 6.37; P = 0.071).

CONCLUSIONS

The survival of implants placed in the maxilla, with smooth collar, and late-onset of infection was higher than those placed in the mandible, with a rough collar and early onset of infection. In general, signs of infection after dental implant placement compromises the survival rate of the affected fixtures.

摘要

背景

种植牙术后感染较为罕见,但可能导致种植体早期失败。然而,目前关于这一主题的信息有限。

方法

本回顾性队列研究旨在确定在骨整合期发生术后感染的种植牙失败率可能增加的因素。术后感染被定义为在修复体加载之前,手术区域出现脓液或瘘管,伴有疼痛或压痛、肿胀、发红、发热或发烧。采用 Cox 比例风险回归对数据进行单变量和多变量分析,以检测感染患者种植体失败的预后因素。

结果

种植体植入后发生术后感染的患者患病率为 2.80%(95%置信区间(95%CI):2.04%至 3.83%)。33 例(89.19%)感染患者因抗生素治疗失败而需要手术治疗,65%的感染种植体被取出。单变量分析显示,种植体失败与领口表面之间存在显著相关性(HR:3.12;95%CI:1.16 至 8.41;P=0.014)。Cox 比例风险回归表明,粗糙表面的领口增加了 2.35 倍的失败可能性(95%CI:0.87 至 6.37;P=0.071)。

结论

上颌种植体、光滑领口、感染晚期的种植体存活率高于下颌种植体、粗糙领口、感染早期的种植体存活率。一般来说,种植牙术后出现感染迹象会降低受影响种植体的存活率。

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