Xu J, Zeng X L
Department of Otolaryngology Head and Neck Surgery,the Third Hospital of Dongguan,523000,China.
Department of Otolaryngology Head and Neck Surgery,the Third Hospital of Sun Yat-sen University.
Lin Chuang Er Bi Yan Hou Tou Jing Wai Ke Za Zhi. 2016 Nov;30(22):1796-1799. doi: 10.13201/j.issn.1001-1781.2016.22.013.
To investigate the relationship between high jugular bulb and tinnitus and hearing disorder. Forty-nine inpatient patients with hearing disorder were selected as the case group,and 50 cases as the control group,two groups of patients conducted temporal CT, audiogram to find out the patients who had hearing disorder,and then acoustic immittance, DPOAE, ABR,genetic screening for deafness and tinnitus questionnaire were conducted to the patients with hearing disorder. Sixteen cases of these 99 patients had high jugular bulb,the total incidence was 16.16%, 14 cases in the case group had high jugular bulb, the incidence was 28.57%,only 2 cases in the control group, the incidence was 4.00%, there was significant difference(χ²=11.027,<0.01)between two groups.For the cases group, 8 cases(57.14%) had hearing loss in the high frequencies, 4 cases(28.57%) in the low frequencies,2 cases(14.29%) in all frequencies;all of these 14 cases with high jugular bulb also had different degrees of tinnitus,12 of which had pulsatile tinnitus(85.71%), vascular pulsatile tinnitus was most common type,2 of which had non pulsatile tinnitus(14.29%).Four common deafness genes GJB2, SLC26A4, mtDNA12srRNA and GJB3 9 mutation screening tests showed no positive mutation in both groups. High jugular bulb has higher incidence in patients with hearing disorder,which may be a risk factor for hearing disorder.Attention should be paid to the influence of high jugular bulb in clinical diagnosis and treatment of hearing disorder.
探讨高位颈静脉球与耳鸣及听力障碍之间的关系。选取49例听力障碍住院患者作为病例组,50例作为对照组,两组患者均行颞骨CT、纯音听力测试以找出存在听力障碍的患者,然后对听力障碍患者进行声导抗、畸变产物耳声发射(DPOAE)、听性脑干反应(ABR)、耳聋基因筛查及耳鸣问卷调查。这99例患者中16例存在高位颈静脉球,总发生率为16.16%,病例组14例存在高位颈静脉球,发生率为28.57%,对照组仅2例,发生率为4.00%,两组间差异有统计学意义(χ²=11.027,P<0.01)。病例组中,8例(57.14%)为高频听力损失,4例(28.57%)为低频听力损失,2例(14.29%)为全频听力损失;这14例高位颈静脉球患者均有不同程度耳鸣,其中12例为搏动性耳鸣(85.71%),血管搏动性耳鸣最为常见,2例为非搏动性耳鸣(14.29%)。4种常见耳聋基因GJB2、SLC26A4、线粒体DNA12srRNA及GJB3的突变筛查结果显示两组均无阳性突变。高位颈静脉球在听力障碍患者中发生率较高,可能是听力障碍的一个危险因素。在听力障碍的临床诊疗中应注意高位颈静脉球的影响。