Department of Pediatric Radiology, Hôpital Timone-Enfants, 264, rue Saint-Pierre, 13005 Marseille, France.
Department of Pediatric Radiology, Hôpital Timone-Enfants, 264, rue Saint-Pierre, 13005 Marseille, France.
Diagn Interv Imaging. 2018 Oct;99(10):663-668. doi: 10.1016/j.diii.2018.04.012. Epub 2018 May 28.
To assess the capabilities of a velocity ratio>3 for the diagnosis of Budd-Chiari syndrome (BCS) in children after split liver transplantation using Doppler ultrasonography (DUS).
A total of 28 children who underwent liver transplantation using a split procedure were included. There were 11boys and 17girls with a mean age of 3.8years (range: 0.7-12years). Velocity ratio between blood velocity upstream of the anastomosis and that at the level of the inferior vena cava anastomosis was calculated. Sensitivity, specificity and accuracy of DUS for the diagnosis of BCS were estimated using a velocity ratio>3.
Eight children (8/28; 29%) had BCS and 20 (20/28; 71%) did not have BCS using the standard of reference. A velocity ratio>3 on DUS yielded 88% sensitivity (95% CI: 53-98%), 80% specificity (95% CI: 58-92%) and 82% accuracy (95% CI: 64-92%) for the diagnosis of BCS.
A velocity ratio>3 on DUS is a reliable finding for the diagnosis of BCS in children after split liver transplantation.
使用多普勒超声(DUS)评估肝分裂移植术后儿童布加氏综合征(BCS)诊断中血流速度比值>3 的能力。
共纳入 28 例行肝分裂术的儿童患者。男 11 例,女 17 例,平均年龄 3.8 岁(范围:0.7-12 岁)。计算吻合口上游血流速度与下腔静脉吻合口水平血流速度的比值。使用血流速度比值>3 评估 DUS 对 BCS 诊断的灵敏度、特异度和准确度。
8 例(8/28;29%)儿童存在 BCS,20 例(20/28;71%)儿童无 BCS,参考标准为金标准。DUS 上血流速度比值>3 对 BCS 的诊断灵敏度为 88%(95%CI:53-98%),特异度为 80%(95%CI:58-92%),准确度为 82%(95%CI:64-92%)。
DUS 上血流速度比值>3 是诊断肝分裂移植术后儿童 BCS 的可靠依据。