Capek Lukas, Flynn Cormac, Molitor Martin, Chong Simon, Henys Petr
Technical University of Liberec, Department of Structure and Technologies, Studentska 2, 46117 Liberec 1, Czech Republic.
Waikato Institute of Technology, Private Bag 3036, Hamilton 3240, New Zealand.
Burns. 2018 Sep;44(6):1439-1445. doi: 10.1016/j.burns.2018.05.001. Epub 2018 May 31.
The technique of meshed skin grafting is known since 1960s. It was shown that there is a difference between the declared and real expansion ratio of the skin meshed graft. We hypothesize that the orientation of the Langer's lines in a split thickness skin graft is a key parameter in the resulting expansion ratio.
The skin graft meshing process was analyzed in two steps. In the first step, ex vivo uniaxial tests of human skin were performed. This served as an input for the constitutive model used for numerical simulations. In the second step, finite element analyses were performed so that stress distributions and expansion ratios could be determined.
It was shown that peaks of true stress tended to be concentrated around the vertex of the mesh pattern region for all cases. The declared expansion was impossible to obtain for all expansion ratios having the meshing incision perpendicular to the Langer's lines. The highest difference between declared and real expansion ratio reaches 37%.
With regard to literature dealing with expansion of skin grafts by meshing, a high scatter amongst data results is observed. This finding was also explained by our research, demonstrating the significance of Langer's lines and their relative orientation to the direction of meshing.
网状植皮技术自20世纪60年代就已为人所知。研究表明,皮肤网状移植物的宣称扩张率与实际扩张率存在差异。我们假设,在中厚皮片中朗格线的方向是决定最终扩张率的关键参数。
对皮肤移植的网状化过程分两步进行分析。第一步,对人体皮肤进行离体单轴测试。这为用于数值模拟的本构模型提供了输入数据。第二步,进行有限元分析,以便确定应力分布和扩张率。
结果表明,在所有情况下,真实应力峰值往往集中在网格图案区域的顶点周围。对于所有使网状切口垂直于朗格线的扩张率,都无法获得宣称的扩张效果。宣称扩张率与实际扩张率之间的最大差异达到37%。
关于通过网状化扩张皮肤移植物的文献,观察到数据结果存在很大差异。我们的研究也解释了这一发现,证明了朗格线及其与网状化方向的相对取向的重要性。