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用于记录抗生素对微生物细胞作用的电光检测法。

Electrooptical Assay for Record of Antibiotic Action on Microbial Cells.

作者信息

Guliy O I, Bunin V D, Ignatov O V

出版信息

Antibiot Khimioter. 2016 Aug;61:3-13.

Abstract

Development of rapid and sensitive procedures for determination of microbial resistance to antibiotics is one of the most urgent trends in microbiology. The problem is shown to be solved by using electrooptical assay based on change of the electrophysical properties of suspended bacterial cells exposed to antibiotics with different mechanisms of action. Possible determination of the microbial cell susceptibility to antibiotics and their antibacterial activity is demonstrated. The results showed the procedure of electrooptical assay to be prospective in solving the problem of the microbiol cells antibiotic susceptibility in microbiology, medicine and veterinary.

摘要

开发快速灵敏的微生物对抗生素耐药性测定方法是微生物学中最紧迫的趋势之一。结果表明,基于具有不同作用机制的抗生素作用下悬浮细菌细胞电物理性质变化的电光测定法可解决该问题。证明了测定微生物细胞对抗生素的敏感性及其抗菌活性的可能性。结果表明,电光测定法在解决微生物学、医学和兽医学中微生物细胞抗生素敏感性问题方面具有前瞻性。

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