Lee Hyeok Dong, Lee Sung Young, Cho Young-Shin, Han Seung Hoon, Park Si-Bog, Lee Kyu Hoon
Department of Rehabilitation Medicine, Hanyang University College of Medicine, Seoul, Republic of Korea.
Medicine (Baltimore). 2018 Jun;97(23):e11051. doi: 10.1097/MD.0000000000011051.
Peripheral neuropathy is a rare complication of carbon monoxide intoxication. Peripheral neuropathy following carbon monoxide intoxication is known to completely recover within a few months.
A 40-year-old man complained of motor weakness and hypoesthesia of the right lower extremity with swelling of his right thigh after carbon monoxide intoxication resulting from a suicide attempt.
Following nerve conduction and electromyographic studies, the patient was diagnosed with sciatic neuropathy with severe axonopathy. Clinical and laboratory findings led to a diagnosis of rhabdomyolysis.
The patient was treated conservatively for rhabdomyolysis and underwent comprehensive rehabilitation for sciatic neuropathy during hospitalization.
After discharge, he underwent serial follow-up tests with nerve conduction and electromyographic studies, which showed prolonged persistence of sciatic neuropathy; however, he showed significant improvement at his 26-month post-discharge follow-up.
Patients presenting with peripheral neuropathy secondary to carbon monoxide intoxication may show variable recovery periods; however, a favorable prognosis can be expected regardless of the concomitant occurrence of rhabdomyolysis and/or compartment syndrome.
周围神经病变是一氧化碳中毒的一种罕见并发症。已知一氧化碳中毒后的周围神经病变会在数月内完全恢复。
一名40岁男性在自杀未遂导致一氧化碳中毒后，出现右下肢运动无力、感觉减退以及右大腿肿胀。
经神经传导和肌电图检查，该患者被诊断为坐骨神经病变伴严重轴索性病变。临床和实验室检查结果确诊为横纹肌溶解症。
患者因横纹肌溶解症接受了保守治疗，并在住院期间接受了坐骨神经病变的综合康复治疗。
出院后，他接受了一系列神经传导和肌电图随访检查，结果显示坐骨神经病变持续时间延长；然而，在出院后26个月的随访中，他有显著改善。
一氧化碳中毒继发周围神经病变的患者恢复时间可能各不相同；不过，无论是否同时发生横纹肌溶解症和/或骨筋膜室综合征，预后都有望良好。
