Gonie Alemayehu, Bekele Kebebe
Department of Nursing, School of Health Sciences, Goba Referral Hospital, Madda Walabu University, Bale-Goba, Ethiopia.
Department of Surgery, School of Medicine, Goba Referral Hospital, Madda Walabu University, Bale-Goba, Ethiopia.
Int Med Case Rep J. 2018 May 29;11:129-131. doi: 10.2147/IMCRJ.S158074. eCollection 2018.
Gastrointestinal tuberculosis (TB) accounts for 3% of extrapulmonary TB. Tuberculous appendicitis is a rare type of abdominal TB and is seen in only 0.1%-0.3% of cases. Diagnosis is usually made after histopathologic examination of the appendectomy specimen. In Ethiopia, there had been no previous report of perforated appendicular TB, and to our knowledge, this is the first case report of a patient with perforated tuberculous appendicitis to be presented.
A 22-year-old male patient presented with complaints of severe abdominal cramp, periumbilical pain, nausea, 2 episodes of nonbilious vomiting, as well as high-grade fever. Upon admission, abdominal examination revealed direct tenderness below the umbilicus bilaterally and rebound tenderness over the right lower quadrant of the abdomen. The peritoneal cavity was opened through a lower midline incision, and a perforated appendix at the base was found.
From the resected appendix, a sample biopsy was sent for histopathology, and the histological picture revealed granulomatous caseification lesion in the body of the appendix, but no granulomatous lesions elsewhere in the bowel or omentum. Based on these findings, the final diagnosis of perforated tuberculous appendicitis was made. After surgery, the patient started anti-TB treatment on the fourth postoperative day and continued therapy for 6 months, and marked clinical recovery has been observed to date.
Perforated tuberculous appendicitis was diagnosed only after histopathologic examination of the resected appendix. Hence, TB, a highly prevalent disease in low-income countries, should always be considered in patients with nonspecific abdominal clinical sign and symptoms. It is also suggested that all specimens from perforated appendicitis be subjected to histopathologic examination.
胃肠道结核(TB)占肺外结核的3%。结核性阑尾炎是腹部结核的一种罕见类型,仅见于0.1%-0.3%的病例。诊断通常在阑尾切除标本的组织病理学检查后作出。在埃塞俄比亚,此前没有穿孔性阑尾结核的报告,据我们所知,这是首例关于穿孔性结核性阑尾炎患者的病例报告。
一名22岁男性患者主诉严重腹痛、脐周疼痛、恶心、非胆汁性呕吐2次以及高热。入院时,腹部检查发现双侧脐下有直接压痛,右下腹有反跳痛。经下腹部正中切口打开腹腔,发现阑尾根部穿孔。
从切除的阑尾中取样本进行组织病理学检查,组织学图像显示阑尾体部有肉芽肿性干酪样病变,但肠道或网膜其他部位未见肉芽肿性病变。基于这些发现,最终诊断为穿孔性结核性阑尾炎。手术后,患者在术后第四天开始抗结核治疗,并持续治疗6个月,迄今为止已观察到明显的临床康复。
穿孔性结核性阑尾炎仅在对切除的阑尾进行组织病理学检查后才得以诊断。因此,对于有非特异性腹部临床症状和体征的患者,应始终考虑结核病,因为结核病在低收入国家非常普遍。还建议对所有穿孔性阑尾炎标本进行组织病理学检查。