重型β地中海贫血所致气肿性骨髓炎。

Emphysematous osteomyelitis caused by in beta thalassemia major.

作者信息

Doctor P N, Verma M, Varaiya A, Merchant R H

机构信息

Department of Paediatrics, Nanavati Super Speciality Hospital, Vile Parle West, Mumbai, Maharashtra, India.

Department of Radiology, Nanavati Super Speciality Hospital, Vile Parle West, Mumbai, Maharashtra, India.

出版信息

J Postgrad Med. 2019 Jan-Mar;65(1):41-43. doi: 10.4103/jpgm.JPGM_689_17.

DOI:10.4103/jpgm.JPGM_689_17

PMID:29882519

原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6380132/

Abstract

There have been various cases of salmonella osteomyelitis reported in sickle cell anemia. We present a case of emphysematous osteomyelitis caused by Salmonella typhi in a 29-year-old beta thalassemia major patient. Diagnosis of emphysematous osteomyelitis was confirmed by computed tomography and magnetic resonance imaging, and culture of pus drained during surgical debridement confirmed the causative microorganism, Salmonella typhi. Antimicrobials were given according to microbiological sensitivity for a period of 8 weeks. Our patient also received hyperbaric oxygen therapy. At the end of therapy, he was afebrile and laboratory parameters normalized with a residual joint deformity which developed within 3 months.

摘要

镰状细胞贫血患者中曾有多种沙门氏菌骨髓炎病例的报道。我们报告一例29岁重型β地中海贫血患者发生的由伤寒沙门氏菌引起的气性骨髓炎。气性骨髓炎的诊断通过计算机断层扫描和磁共振成像得以证实，手术清创时引流脓液的培养确定了致病微生物为伤寒沙门氏菌。根据微生物敏感性给予抗菌药物治疗8周。我们的患者还接受了高压氧治疗。治疗结束时，他不再发热，实验室指标恢复正常，但在3个月内出现了残留关节畸形。