垂体转移瘤病例的诊断、治疗及治疗效果

Diagnosis, Therapy, and Therapeutic Effects in Cases of Pituitary Metastasis.

作者信息

Zhao Yi, Lian Wei, Xing Bing, Feng Ming, Liu Xiaohai, Wang Renzhi, Zhou Weixun

机构信息

Department of Neurosurgery, Peking Union Medical College Hospital, Chinese Academy of Medical Science & Peking Union Medical College, Beijing, China.

出版信息

World Neurosurg. 2018 Sep;117:122-128. doi: 10.1016/j.wneu.2018.05.205. Epub 2018 Jun 5.

DOI:10.1016/j.wneu.2018.05.205

PMID:29883826

Abstract

OBJECTIVE

This study aimed to summarize the diagnosis, therapy, and prognosis of pituitary metastasis.

METHODS

Ten patients from the Department of Neurosurgery of the Peking Union Medical College Hospital from April 1997 to August 2014 were retrospectively analyzed.

RESULTS

The participants included 7 males (70%) and 3 females (30%), with an average age of 60.4 years. The most common initial clinical feature was visual disability (50%). The postoperative pathology reports indicated 1 case (10%) of metastatic large-cell pulmonary carcinoma, 2 cases (20%) of metastatic small cell pulmonary carcinoma, 2 cases (20%) of clear cell renal carcinoma metastasis, and 5 cases (50%) of metastasis of adenocarcinomas from different areas. All the patients underwent a thorough follow-up, and the average survival was 144 days.

CONCLUSIONS

Pituitary metastasis is a rare disease. Its diagnosis depends on the clinical manifestations and radiologic results. The primary therapeutic method is surgery and subsequent radiotherapy and chemotherapy; however, the prognosis of this disease is poor.

摘要

目的

本研究旨在总结垂体转移瘤的诊断、治疗及预后情况。

方法

回顾性分析1997年4月至2014年8月北京协和医院神经外科收治的10例患者。

结果

参与者包括7名男性（70%）和3名女性（30%），平均年龄60.4岁。最常见的初始临床特征为视力障碍（50%）。术后病理报告显示，1例（10%）为转移性大细胞肺癌，2例（20%）为转移性小细胞肺癌，2例（20%）为透明细胞肾癌转移，5例（50%）为不同部位腺癌转移。所有患者均接受了全面随访，平均生存期为144天。