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无接触经巩膜-脉络膜平面光照明实现免散瞳超广角眼底照相

Contact-free trans-pars-planar illumination enables snapshot fundus camera for nonmydriatic wide field photography.

机构信息

Department of Bioengineering, University of Illinois at Chicago, Chicago, IL, USA.

Department of Ophthalmology and Visual Sciences, University of Illinois at Chicago, Chicago, IL, USA.

出版信息

Sci Rep. 2018 Jun 8;8(1):8768. doi: 10.1038/s41598-018-27112-x.

Abstract

In conventional fundus photography, trans-pupillary illumination delivers illuminating light to the interior of the eye through the peripheral area of the pupil, and only the central part of the pupil can be used for collecting imaging light. Therefore, the field of view of conventional fundus cameras is limited, and pupil dilation is required for evaluating the retinal periphery which is frequently affected by diabetic retinopathy (DR), retinopathy of prematurity (ROP), and other chorioretinal conditions. We report here a nonmydriatic wide field fundus camera employing trans-pars-planar illumination which delivers illuminating light through the pars plana, an area outside of the pupil. Trans-pars-planar illumination frees the entire pupil for imaging purpose only, and thus wide field fundus photography can be readily achieved with less pupil dilation. For proof-of-concept testing, using all off-the-shelf components a prototype instrument that can achieve 90° fundus view coverage in single-shot fundus images, without the need of pharmacologic pupil dilation was demonstrated.

摘要

在传统眼底摄影中,经瞳孔照明通过瞳孔的周边区域将照明光传输到眼睛内部,并且仅瞳孔的中心部分可用于收集成像光。因此,传统眼底相机的视场受限,并且需要散瞳来评估经常受到糖尿病性视网膜病变 (DR)、早产儿视网膜病变 (ROP) 和其他脉络膜视网膜疾病影响的视网膜周边。我们在此报告一种非散瞳广角眼底相机,它采用经平面外照明,通过平面外区域(瞳孔外的区域)传输照明光。经平面外照明使整个瞳孔仅用于成像目的,因此可以在较小的瞳孔扩张下轻松实现广角眼底摄影。为了进行概念验证测试,使用现成的组件,展示了一种原型仪器,该仪器可以在单次眼底图像中实现 90°眼底视图覆盖,而无需药物散瞳。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/8e02/5993752/cc38ca450364/41598_2018_27112_Fig1_HTML.jpg

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