化学形态分析与金属组学

Chemical Speciation and Metallomics.

机构信息

Universidade Estadual de Campinas - Unicamp, Campinas, São Paulo, Brazil.

Spectrometry, Sample Preparation and Mechanization Group (GEPAM), Department of Analytical Chemistry, Institute of Chemistry, University of Campinas (UNICAMP), Campinas, São Paulo, Brazil.

出版信息

Adv Exp Med Biol. 2018;1055:183-211. doi: 10.1007/978-3-319-90143-5_8.

DOI:10.1007/978-3-319-90143-5_8

PMID:29884966

Abstract

Chemical speciation approaches is an inherent part of metallomics, once metals/metalloids and organic structures need to be currently evaluated for attaining metallomics studies. Then, this chapter focuses on the applications of the chemical speciation applied to the human health risk, food and human diet, drugs, forensic, nanoscience, and geological metallomics, also pointing out the advances in such area. Some aspects regarding sample preparation is commented along this chapter, and some strategies for maintaining the integrity of the metallomics information are also emphasized.

摘要

化学形态分析方法是金属组学的固有组成部分，因为当前需要评估金属/类金属和有机结构，以开展金属组学研究。然后，本章重点介绍化学形态分析在人类健康风险、食品和人类饮食、药物、法医学、纳米科学和地质金属组学中的应用，同时指出该领域的进展。本章还对样品制备的一些方面进行了评论，并强调了保持金属组学信息完整性的一些策略。