Suppr超能文献

[双气囊小肠镜下克罗恩病的特征]

[Characteristics of Crohn's disease under 
double balloon enteroscopy].

作者信息

Jia Jia, Liu Rui, Liu Xiangjie, Shen Shourong, Guo Qin

机构信息

Department of Gastroenterology; Hunan Key Laboratory of Non-resolving Inflammation and Cancer, 
Third Xiangya Hospital, Central South University, Changsha 410013, China.

出版信息

Zhong Nan Da Xue Xue Bao Yi Xue Ban. 2018 May 28;43(5):494-499. doi: 10.11817/j.issn.1672-7347.2018.05.006.

Abstract

To observe ulcer characteristics of Crohn's disease under double balloon enteroscopy, and to evaluate the correlation between endoscopic severity and clinical manifestations.
 Methods: A prospective, observational study from July 2015 to December 2016 in the Third Xiangya Hospital, Central South University, we selected 45 patients with positive double-balloon enteroscopy (DBE) and confirmed Crohn's disease. Two digestive internal physician observed the ulcer characteristics of Crohn's disease under double balloon enteroscopy, and gave a simple endoscopic score for CD (SES-CD). We analyzed the correlation between SES-CD and Crohn's disease activity index (CDAI).
 Results: DBE indicated 24 patient ulcers (53.33%) locating at the end of the ileum, 5 (11.11%) locating at ileocolon, 16 (35.56%) locating at upper gatrointestinal tract and they did not affect the end of the ileum. Among them, 8 cases (17.78%) affected only jejunum. Thirty-two patients with longitudinal ulcers in Crohn's disease, accounting for 71.11%. There was no correlation between SES-CD score and CDAI score (r=0.237, P=0.136).
 Conclusion: The ulcerative appearance in Crohn's disease were diverse under double balloon enteroscopy. Crohn's disease could only affect the upper gastrointestinal tract or jejunum. The unwounded ileum and ileocecal valve couldn't be a sign to exclude Crohn's disease. CDAI score couldn't fully assess the prognosis of Crohn's disease.

摘要

观察克罗恩病在双气囊小肠镜下的溃疡特征,并评估内镜严重程度与临床表现之间的相关性。

方法

2015年7月至2016年12月在中南大学湘雅三医院进行的一项前瞻性观察研究,我们选取了45例双气囊小肠镜(DBE)检查阳性且确诊为克罗恩病的患者。两名消化内科医生在双气囊小肠镜下观察克罗恩病的溃疡特征,并对克罗恩病给出一个简单的内镜评分(SES-CD)。我们分析了SES-CD与克罗恩病活动指数(CDAI)之间的相关性。

结果

DBE显示24例患者溃疡(53.33%)位于回肠末端,5例(11.11%)位于回结肠,16例(35.56%)位于上消化道且未累及回肠末端。其中,8例(17.78%)仅累及空肠。32例克罗恩病患者有纵行溃疡,占71.11%。SES-CD评分与CDAI评分之间无相关性(r=0.237,P=0.136)。

结论

双气囊小肠镜下克罗恩病的溃疡表现多样。克罗恩病可仅累及上消化道或空肠。未受累的回肠及回盲瓣不能作为排除克罗恩病的依据。CDAI评分不能完全评估克罗恩病的预后。

文献AI研究员

20分钟写一篇综述,助力文献阅读效率提升50倍。

立即体验

用中文搜PubMed

大模型驱动的PubMed中文搜索引擎

马上搜索

文档翻译

学术文献翻译模型,支持多种主流文档格式。

立即体验