Institute of Clinical Neurophysiology, Division of Neurology, University Medical Centre Ljubljana, Slovenia.
Clin Neurophysiol. 2018 Aug;129(8):1763-1769. doi: 10.1016/j.clinph.2018.04.753. Epub 2018 Jun 1.
Ulnar neuropathy at the elbow (UNE) consists mainly of two conditions: entrapment under the humeroulnar aponeurosis (HUA) and extrinsic compression in the retrocondylar (RTC) groove. These in our opinion need different treatment: surgical HUA release and avoidance of inappropriate arm positioning, respectively. We treated our UNE patients accordingly, and studied their long-term outcomes.
We invited our cohort of UNE patients to a follow-up examination consisting of history, neurological, electrodiagnostic (EDx) and ultrasonographic (US) examinations performed by four blinded investigators.
At a mean follow-up time of 881 days, we performed a complete evaluation in 117 of 165 (65%) patients, with 96 (90%; 35 HUA and 61 RTC) treated according to our recommendations. An improvement was reported by 83% of HUA and 84% of RTC patients. In both groups the ulnar nerve mean compound muscle action potential (CMAP) amplitude, and the minimal motor nerve conduction velocity increased, while the maximal ulnar nerve cross-sectional area (CSA) decreased.
After 2.5 years similar proportions of HUA and RTC patients reported clinical improvement that was supported by improvement in EDx and US findings.
These results suggest that patients with UNE improve following both surgical decompression and non-operative treatment. A clinical trial comparing treatment approaches in neuropathy localised to the HUA and RTC will be needed to possibly confirm our opinion that the therapeutic approach should be tailored according to the presumed aetiology of UNE.
肘管尺神经病变(UNE)主要包括两种情况:肱尺肌腱弓下卡压和髁后沟(RTC)外卡压。这两种情况我们认为需要不同的治疗方法:分别进行肱尺肌腱弓松解和避免不当的手臂位置。我们对相应的 UNE 患者进行了治疗,并研究了他们的长期结果。
我们邀请了我们的 UNE 患者队列进行随访检查,包括由四名盲法调查员进行的病史、神经学、电诊断(EDx)和超声(US)检查。
在平均 881 天的随访中,我们对 165 名患者中的 117 名(65%)进行了完整评估,其中 96 名(90%;35 名 HUA 和 61 名 RTC)根据我们的建议进行了治疗。HUA 组和 RTC 组分别有 83%和 84%的患者报告症状改善。在两组中,尺神经复合肌肉动作电位(CMAP)平均振幅和最小运动神经传导速度增加,而最大尺神经横截面积(CSA)减小。
在 2.5 年后,HUA 和 RTC 患者报告临床改善的比例相似,EDx 和 US 检查结果也支持这一改善。
这些结果表明,UNE 患者在接受手术减压和非手术治疗后都有改善。需要进行一项比较针对肱尺肌腱弓和 RTC 局部神经病变的治疗方法的临床试验,以可能证实我们的观点,即治疗方法应根据 UNE 的假定病因进行定制。