Urinary adenylate kinase activity as a predictor of renal allograft crises.

We examined data on adenylate kinase (EC 2.7.4.3) activity and other clinical chemical values from patients with renal transplants by analysis of variance and discriminant analysis, using various combinations of variables in an attempt to find a predictor of transplant rejection. Some typical data are presented. We conclude that the combination of urinary adenylate kinase and creatinine clearance is the best predictor for identifying patients with transient or destructive renal transplant crises.