急性盆腔炎女性中单纯疱疹病毒的检测

Detection of herpes simplex virus in women with acute pelvic inflammatory disease.

作者信息

Lehtinen M, Rantala I, Teisala K, Heinonen P K, Lehtinen T, Aine R, Miettinen A, Grönroos P, Punnonen R, Leinikki P

出版信息

J Infect Dis. 1985 Jul;152(1):78-82. doi: 10.1093/infdis/152.1.78.

DOI:10.1093/infdis/152.1.78

Abstract

Four women are described with acute salpingitis confirmed by laparoscopy who had herpes simplex virus (HSV) isolated from the cervix or the upper genital tract (endometrium, fallopian tube, or cul-de-sac) or both. None of the patients had overt genital herpes, but one had typical HSV cervitis on a cervicovaginal smear stained with Papanicolaou's stain, one had a significant change in level of antibodies to HSV, and one had an endometrial biopsy specimen positive for HSV antigen. There are at least three potential explanations for these findings: chronic viral shedding, viral reactivation caused by acute pelvic inflammatory disease (PID), or that the PID was actually caused by HSV. Further prospective studies are needed to document the role of HSV in causing PID.

摘要

四名女性经腹腔镜检查确诊为急性输卵管炎，她们的宫颈或上生殖道（子宫内膜、输卵管或直肠子宫陷凹）或两者均分离出单纯疱疹病毒（HSV）。所有患者均无明显的生殖器疱疹，但一名患者在巴氏染色的宫颈阴道涂片上有典型的HSV宫颈炎，一名患者HSV抗体水平有显著变化，一名患者子宫内膜活检标本HSV抗原呈阳性。对于这些发现，至少有三种可能的解释：慢性病毒脱落、急性盆腔炎（PID）引起的病毒再激活，或PID实际上由HSV引起。需要进一步的前瞻性研究来证实HSV在引起PID中的作用。