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尽管接受了规范治疗,妊娠合并子宫颈浸润癌的病程仍进展迅速且预后不良。35岁经产妇的病例报告。

Fast and unfavorable course of invasive cancer of the uterine cervix associated with pregnancy despite of a typical treatment. Case report of 35-year-old pregnant multipara.

作者信息

Pawlowicz P, Dabrowska M

出版信息

Eur J Gynaecol Oncol. 2016 Aug;37(4):558-562.

Abstract

Carcinoma of the cervix is the most common malignancy associated with pregnancy. The frequency of cervical cancer is estimated to range from 1/1,200 to 1/10,000 pregnancies. The symptoms of cervical cancer are not specific and can be mistaken as frequent symptoms associated with other pathologies of pregnancy. The diagnostic procedure is similar to the one which should be proposed to unpregnant women. The treatment of cervical cancer depends on gestational age. The final treatment and further prognosis is carried out after delivery. The authors present the case of a 35-year-old woman at 34 weeks of gestation diagnosed with Stage IB cervical cancer. Treatment was delayed until fetal maturity and an elective cesarean section was performed at 36 weeks' gestation, followed by a radical hysterectomy, bilateral salpingo-oophorectomy, and a pelvic lymphadenectomy. Patient underwent adjuvant radiochemotherapy and brachytherapy. Recurrence of neoplastic process was found after one year.

摘要

宫颈癌是与妊娠相关的最常见恶性肿瘤。据估计,宫颈癌在妊娠中的发生率为1/1200至1/10000。宫颈癌的症状不具有特异性,可能被误诊为与妊娠其他病理状况相关的常见症状。其诊断程序与建议非妊娠女性采用的程序相似。宫颈癌的治疗取决于孕周。最终治疗及进一步预后在分娩后进行。作者报告了一例35岁女性,妊娠34周时被诊断为IB期宫颈癌。治疗推迟至胎儿成熟,妊娠36周时行择期剖宫产,随后行根治性子宫切除术、双侧输卵管卵巢切除术及盆腔淋巴结清扫术。患者接受了辅助放化疗及近距离放疗。一年后发现肿瘤复发。

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