Institute of Evolutionary Biology & Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK.
Institute of Evolutionary Biology & Institute of Immunology and Infection Research, University of Edinburgh, Edinburgh, UK.
Cell Host Microbe. 2018 Jun 13;23(6):695-697. doi: 10.1016/j.chom.2018.05.015.
Successive synchronized cycles of Plasmodium replication in the host's blood causes the symptoms of malaria and fuels disease transmission. In this issue of Cell Host & Microbe, Hirako et al. (2018) reveal that host circadian rhythms of inflammation and metabolism are responsible for the timing of cycles of parasite replication.
疟原虫在宿主血液中连续同步的复制周期导致疟疾症状的出现,并促进疾病传播。在本期《细胞宿主与微生物》中,Hirako 等人(2018)揭示了宿主炎症和代谢的昼夜节律负责寄生虫复制周期的时间安排。