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回肠贮袋肛门吻合术的现状和结果评估:回肠贮袋肛门吻合术注册研究和 2017 年回肠贮袋肛门吻合术报告中的经验教训。

Review of current practice and outcomes following ileoanal pouch surgery: lessons learned from the Ileoanal Pouch Registry and the 2017 Ileoanal Pouch Report.

机构信息

St Mark's Hospital and Academic Institute, London North West University Healthcare NHS Trust, London, UK.

Department of Surgery and Cancer, Imperial College London, London, UK.

出版信息

Colorectal Dis. 2018 Oct;20(10):913-922. doi: 10.1111/codi.14316. Epub 2018 Aug 27.

Abstract

AIM

The second Association of Coloproctology of Great Britain and Ireland (ACPGBI) Ileoanal Pouch Registry (IPR) report was released in July 2017 following a first report in 2012. This article provides a summary of data derived from the most recent IPR report (2017 Ileoanal Pouch Report. https://www.acpgbi.org.uk/content/uploads/2016/07/Ileoanal-Pouch-Report-2017-FINAL.compressed.pdf).

METHOD

The IPR is an electronic database of voluntarily submitted data including patient demographics, disease, intra-operative and postoperative factors submitted by consultant surgeons or delegates. Data up to 31 March 2017 have been analysed for this report.

RESULTS

A total of 5352 pouch operations were carried out at 76 UK and four European centres by 154 surgeons over four decades. Recorded procedures have increased over time but data submission is voluntary and underestimates actual volume. Significant variation exists in institutional volume; 73 centres entered data on patients undergoing pouch surgery during the past 5 years. Of these, 44 centres have submitted ≤ 10 cases, with 10 centres submitting one patient and nine centres two cases. Since 2013, minimal access surgery has been employed in 54% of cases. Rectal dissection was undertaken in the total mesorectal excision plane in 69%. J-pouch configuration was used in 99% of cases and 90% of pouch-anal anastomoses were performed using a stapled technique. Including all years, the IPR rate of pelvic sepsis was 9.4% and the rate of pouch failure was 4.7%.

CONCLUSION

The IPR holds the largest voluntary repository of data on ileoanal pouch surgery. The second report from the IPR records marked refinements in surgical technique over time but also highlights wide variation in institutional caseload and outcome across the UK.

摘要

目的

英国和爱尔兰结直肠外科学会(ACPGBI)的第二次回肠肛管吻合术(Ileoanal Pouch,IAP)注册研究(IAPR)报告于 2017 年 7 月发布,此前于 2012 年发布了第一份报告。本文总结了最近的 IAPR 报告(2017 年回肠肛管吻合术报告。https://www.acpgbi.org.uk/content/uploads/2016/07/Ileoanal-Pouch-Report-2017-FINAL.compressed.pdf)中的数据。

方法

IAPR 是一个电子数据库,其中包含患者人口统计学、疾病、术中及术后因素等自愿提交的数据,由顾问外科医生或代表提交。本报告分析了截至 2017 年 3 月 31 日的数据。

结果

在过去的四十年中,154 位外科医生在 76 家英国和 4 家欧洲中心共进行了 5352 例 IAP 手术。随着时间的推移,记录的手术数量有所增加,但数据提交是自愿的,因此低估了实际数量。机构间的手术量存在显著差异;73 家中心提供了过去 5 年内接受 IAP 手术的患者数据。其中,44 家中心提交的病例数≤10 例,10 家中心仅提交 1 例,9 家中心提交 2 例。自 2013 年以来,微创外科手术在 54%的病例中得到应用。直肠解剖在全直肠系膜切除平面进行,占 69%。99%的病例使用 J 袋结构,90%的袋肛吻合术采用吻合器技术。包括所有年份,IAPR 记录的盆腔感染率为 9.4%, pouch 失败率为 4.7%。

结论

IAPR 是最大的 IAP 手术数据自愿存储库。IAPR 的第二份报告记录了随着时间的推移,手术技术的显著改进,但也突出了英国各地机构手术量和结果的广泛差异。

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