Fasciana Teresa, Colomba Claudia, Cervo Adriana, Di Carlo Paola, Scarlata Francesco, Mascarella Chiara, Giammanco Anna, Cascio Antonio
Department of Sciences for Health Promotion and Mother and Child care "G. D'Alessandro", University of Palermo, Palermo, Italy.
Infez Med. 2018 Jun 1;26(2):167-170.
Mycetoma (or "madura foot") is characterized by deformation, cutaneous lesions, infection of tissues extending from the cutaneous layer to the underlying fascia, and an indolent course. A number of fungal or bacterial agents that are introduced through traumatic inoculation can be responsible for the disease, but Actinomadura madurae is among the most common agents of mycetoma occurring worldwide. We report a case of madura foot caused by A. madurae in an immunocompetent young Somali man who was admitted with a diagnosis of skin and soft tissue infection of the left foot with osteomyelitis. The present report emphasizes the importance of the knowledge of this infection, which is sporadic but problematic to treat and, above all, difficult to diagnose. Moreover, a multidisciplinary approach with involvement of an infectious diseases specialist with experience in tropical diseases and a microbiology unit performing rapid molecular diagnostic tests is required for early diagnosis and an optimal antibiotic therapy.
足菌肿(或“马杜拉足”)的特征为畸形、皮肤损害、从皮肤层延伸至深层筋膜的组织感染以及病程缓慢。多种通过创伤接种进入人体的真菌或细菌病原体可引发该病,但马杜拉放线菌是全球范围内引起足菌肿最常见的病原体之一。我们报告了一例由马杜拉放线菌引起的马杜拉足病例,患者为一名免疫功能正常的年轻索马里男性,因左足皮肤及软组织感染伴骨髓炎入院。本报告强调了了解这种感染的重要性,该感染虽为散发性,但治疗困难,最重要的是难以诊断。此外,早期诊断和优化抗生素治疗需要多学科方法,包括有热带病经验的传染病专家和进行快速分子诊断检测的微生物学部门的参与。