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一期气管及环气管节段切除端端吻合术:结果、并发症及危险因素

Single-stage tracheal and cricotracheal segmental resection with end-to-end anastomosis: Outcome, complications, and risk factors.

作者信息

Hentze Malene, Schytte Sten, Pilegaard Hans, Klug Tejs Ehlers

机构信息

Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Denmark.

Department of Otorhinolaryngology, Head and Neck Surgery, Aarhus University Hospital, Denmark.

出版信息

Auris Nasus Larynx. 2019 Feb;46(1):122-128. doi: 10.1016/j.anl.2018.06.001. Epub 2018 Jun 19.

Abstract

OBJECTIVE

Management of tracheal stenosis remains controversial. Endoscopic interventions commonly provide immediate relief of symptoms, but are associated with high recurrence rates. In contrast, high success rates have been reported in patients undergoing tracheal resection. However, well-defined indications and contraindications for tracheal resection are lacking and previous studies commonly ignore patient-related outcomes (e.g. dyspnoea). We aimed to evaluate the outcome of tracheal resection at our institution and identify risk factors for complications.

METHODS

All adult patients undergoing tracheal resection at Aarhus University Hospital between January 2009 and September 2016 were included RESULTS: Twenty-seven patients were included. The most frequent aetiologies for tracheal stenosis were previous tracheostomy (n=8), prolonged intubation (n=3), a combination of the two (n=5), and intraluminal tumour (n=7). Sixteen patients underwent high tracheal resection, seven patients low tracheal resection, and four patients partial cricotracheal resection. Surgical success (no dyspnoea and no need for additional intervention) was achieved in 74% of patients. Four of six patients undergoing resection because of malignant disease were recurrence-free during the follow-up period. Fifteen (56%) patients suffered complications (transient or permanent). Four (15%) patients had recurrent stenosis and underwent reintervention. Other permanent complications included idiopathic hoarseness (15%), unilateral recurrent nerve palsy (11%), and dysphagia (7%). Previous treatment (endoscopic and open surgery) (OR=5.5, p=0.06) and chronic diseases (OR=8.3, p=0.02) were associated with increased risk for complications.

CONCLUSIONS

Tracheal resection was efficient treatment for the alleviation of dyspnoea in adults with tracheal stenosis. However, complications were frequent and careful preoperative patient selection and information are crucial.

摘要

目的

气管狭窄的治疗仍存在争议。内镜干预通常能立即缓解症状,但复发率较高。相比之下,气管切除患者的成功率较高。然而,气管切除明确的适应证和禁忌证尚缺乏,既往研究通常忽略患者相关结局(如呼吸困难)。我们旨在评估我院气管切除的结局,并确定并发症的危险因素。

方法

纳入2009年1月至2016年9月在奥胡斯大学医院接受气管切除的所有成年患者。结果:共纳入27例患者。气管狭窄最常见的病因是既往气管切开术(n = 8)、长期插管(n = 3)、两者并存(n = 5)和腔内肿瘤(n = 7)。16例患者接受高位气管切除,7例患者接受低位气管切除,4例患者接受部分环状气管切除。74%的患者手术成功(无呼吸困难且无需额外干预)。6例因恶性疾病接受切除的患者中有4例在随访期间无复发。15例(56%)患者出现并发症(短暂或永久性)。4例(15%)患者出现复发性狭窄并接受再次干预。其他永久性并发症包括特发性声音嘶哑(15%)、单侧喉返神经麻痹(11%)和吞咽困难(7%)。既往治疗(内镜和开放手术)(OR = 5.5,p = 0.06)和慢性疾病(OR = 8.3,p = 0.02)与并发症风险增加相关。

结论

气管切除是缓解成人气管狭窄患者呼吸困难的有效治疗方法。然而,并发症频发,术前仔细选择患者并提供信息至关重要。

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