正在构建代码：发育过程中的神经编码。

Code Under Construction: Neural Coding Over Development.

机构信息

Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia.

Queensland Brain Institute, University of Queensland, Brisbane, QLD 4072, Australia; School of Mathematics and Physics, University of Queensland, Brisbane, QLD 4072, Australia.

出版信息

Trends Neurosci. 2018 Sep;41(9):599-609. doi: 10.1016/j.tins.2018.05.011. Epub 2018 Jun 20.

DOI:10.1016/j.tins.2018.05.011

PMID:29935867

Abstract

Developing animals must begin to interact with the world before their neural development is complete. This means they must build neural codes appropriate for turning sensory inputs into motor outputs adaptively as their neural hardware matures. We review some recent progress in the understanding of the relationship between neural coding and neural circuit development. We focus particularly on neural coding in the context of topographic maps and spontaneous activity, as well as receptive field and circuit development, drawing on examples from both mammalian visual cortex and fish optic tectum. Overall we suggest that neural coding strategies during development may be highly dynamic.

摘要

发育中的动物在其神经系统发育完全之前，就必须开始与外界环境相互作用。这意味着它们必须构建适合的神经编码，以便在神经硬件成熟的过程中，自适应地将感觉输入转化为运动输出。我们回顾了在理解神经编码和神经回路发育之间关系方面的一些最新进展。我们特别关注地形映射和自发性活动背景下的神经编码，以及感受野和回路发育，同时借鉴了哺乳动物视觉皮层和鱼类视顶盖的例子。总的来说，我们认为发育过程中的神经编码策略可能是高度动态的。