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血管栓塞与孤立性脾损伤的脾脏挽救之间的关联。

The association between angioembolization and splenic salvage for isolated splenic injuries.

作者信息

Rosenberg Graeme M, Weiser Thomas G, Maggio Paul M, Browder Timothy D, Tennakoon Lakshika, Spain David A, Staudenmayer Kristan L

机构信息

Stanford University, Department of Surgery, Section of Acute Care Surgery, Stanford, California.

出版信息

J Surg Res. 2018 Sep;229:150-155. doi: 10.1016/j.jss.2018.03.013. Epub 2018 Apr 25.

Abstract

BACKGROUND

Recent data suggest improved splenic salvage rates when angioembolization (AE) is routinely employed for high-grade splenic injuries; however, protocols and salvage rates vary among centers.

MATERIALS/METHODS: Adult patients with isolated splenic injuries were identified using the National Trauma Data Bank, 2013-2014. Patients were excluded if they underwent immediate splenectomy or died in the emergency department. To characterize patterns of AE, trauma centers were grouped into quartiles based on frequency of AE use. Unadjusted analyses and mixed-effects logistical regression controlling for center effects were performed.

RESULTS

Five thousand and ninety three adult patients were identified. Overall, 705 (13.8%) underwent AE and 290 (5.7%) required a splenectomy. In unadjusted comparisons, splenectomy rates were lower for patients with severe spleen injuries who underwent AE (7% versus 11%, P = 0.02). In mixed-effect logistical regression patients with severe splenic injuries undergoing AE had a lower odds ratio (OR) for splenectomy (OR = 0.67, P = 0.04). Patients treated at centers in the highest quartile of AE use had a lower OR for splenectomy (OR = 0.58, P = 0.02).

CONCLUSIONS

The use of AE in patients with isolated severe splenic injuries is associated with decreased splenectomy rates. There is an association between centers that perform AE frequently and reduced splenectomy rates.

摘要

背景

近期数据表明,对于高级别脾损伤常规采用血管栓塞术(AE)时,脾脏挽救率有所提高;然而,各中心的方案和挽救率有所不同。

材料/方法:利用2013 - 2014年国家创伤数据库识别出单纯脾损伤的成年患者。如果患者接受了即刻脾切除术或在急诊科死亡,则将其排除。为了描述AE的模式,根据AE使用频率将创伤中心分为四分位数组。进行了未调整分析以及控制中心效应的混合效应逻辑回归分析。

结果

共识别出5093例成年患者。总体而言,705例(13.8%)接受了AE,290例(5.7%)需要进行脾切除术。在未调整的比较中,接受AE的严重脾损伤患者的脾切除率较低(7%对11%,P = 0.02)。在混合效应逻辑回归分析中,接受AE的严重脾损伤患者脾切除的比值比(OR)较低(OR = 0.67,P = 0.04)。在AE使用频率最高的四分位数组中心接受治疗的患者脾切除的OR较低(OR = 0.58,P = 0.02)。

结论

在单纯严重脾损伤患者中使用AE与脾切除率降低相关。频繁进行AE的中心与降低的脾切除率之间存在关联。

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