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30 岁及以下患者初次全髋关节置换术的 10 年生存率。

Ten-year survivorship of primary total hip arthroplasty in patients 30 years of age or younger.

机构信息

Department of Orthopaedics, University of Utah, Salt Lake City, Utah, USA.

出版信息

Bone Joint J. 2018 Jul;100-B(7):867-874. doi: 10.1302/0301-620X.100B7.BJJ-2017-1603.R1.

Abstract

AIMS

For this retrospective cohort study, patients aged ≤ 30 years (very young) who underwent total hip arthroplasty (THA) were compared with patients aged ≥ 60 years (elderly) to evaluate the rate of revision arthroplasty, implant survival, the indications for revision, the complications, and the patient-reported outcomes.

PATIENTS AND METHODS

We retrospectively reviewed all patients who underwent primary THA between January 2000 and May 2015 from our institutional database. A total of 145 very young and 1359 elderly patients were reviewed. The mean follow-up was 5.3 years (1 to 18). Logistic generalized estimating equations were used to compare characteristics and the revision rate. Survival was evaluated using Kaplan-Meier curves and hazard rates were created using Cox regression.

RESULTS

The overall revision rate was 11% (16/145) in the very young and 3.83% (52/1359) in the elderly groups (odds ratio (OR) 2.58, 95% confidence interval (CI) 1.43 to 4.63). After adjusting for the American Society of Anesthesiologists (ASA) score, gender, and a history of previous surgery in a time-to-event model, the risk of revision remained greater in the very young (adjusted hazard ratio (HR) 2.48, 95% CI 1.34 to 4.58). Survival at ten years was 82% (95% CI, 71 to 89) in the very young and 96% (95% CI, 94 to 97) in the elderly group (p < 0.001). The very young had a higher rate of revision for complications related to metal-on-metal (MoM) bearing surfaces (p < 0.001). At last follow-up, the very young group had higher levels of physical function (p = 0.002), lower levels of mental health (p = 0.001), and similar levels of pain (p = 0.670) compared with their elderly counterparts.

CONCLUSION

The overall revision rate was greater in very young THA patients. This was largely explained by the use of MoM bearings. Young patients with non-MoM bearings had high survivorship with similar complication profiles to patients aged ≥ 60 years. Cite this article: Bone Joint J 2018;100-B:867-74.

摘要

目的

本回顾性队列研究比较了≤30 岁(非常年轻)和≥60 岁(老年)接受全髋关节置换术(THA)的患者,以评估翻修率、假体生存率、翻修指征、并发症和患者报告的结果。

方法

我们回顾性分析了 2000 年 1 月至 2015 年 5 月期间我院数据库中所有接受初次 THA 的患者。共回顾了 145 例非常年轻的患者和 1359 例老年患者。平均随访时间为 5.3 年(1 至 18 年)。采用逻辑广义估计方程比较特征和翻修率。采用 Kaplan-Meier 曲线评估生存率,并采用 Cox 回归创建危险率。

结果

非常年轻组的总体翻修率为 11%(16/145),老年组为 3.83%(52/1359)(比值比(OR)2.58,95%置信区间(CI)1.43 至 4.63)。在时间事件模型中,调整美国麻醉医师协会(ASA)评分、性别和既往手术史后,非常年轻组的翻修风险仍然更高(校正后的危险比(HR)2.48,95%CI 1.34 至 4.58)。非常年轻组的 10 年生存率为 82%(95%CI,71 至 89),老年组为 96%(95%CI,94 至 97)(p<0.001)。非常年轻组因金属对金属(MoM)轴承表面相关并发症而导致翻修的比例更高(p<0.001)。末次随访时,非常年轻组的身体功能评分更高(p=0.002),心理健康评分更低(p=0.001),疼痛评分相似(p=0.670)。

结论

非常年轻的 THA 患者总体翻修率更高。这在很大程度上归因于 MoM 轴承的使用。非 MoM 轴承的年轻患者具有较高的生存率,并发症谱与≥60 岁患者相似。

参考文献

Bone Joint J 2018;100-B:867-74.

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