硬膜外镇痛与每日 3 次皮下肝素用于伴有急性术后疼痛的癌症患者。
Epidural Analgesia and Subcutaneous Heparin 3 Times Daily in Cancer Patients With Acute Postoperative Pain.
机构信息
From the Departments of Anesthesiology and Perioperative Medicine.
Pain Medicine, The University of Texas MD Anderson Cancer Center, Houston, Texas.
出版信息
Anesth Analg. 2018 Oct;127(4):e57-e59. doi: 10.1213/ANE.0000000000003603.
The use of epidural analgesia in conjunction with subcutaneous administration of unfractionated heparin 3 times per day could increase the risk of spinal epidural hematoma, but insufficient patient experience data exist to determine this. We retrospectively reviewed the incidence of spinal epidural hematoma in 3705 cases at our institution over a 7-year period of patients receiving acute postoperative epidural analgesia and heparin 3 times per day. No cases of spinal epidural hematoma were reported (95% CI, 0-0.0009952).
硬膜外镇痛联合每日皮下给予非肝素 3 次可能会增加发生脊柱硬膜外血肿的风险，但目前尚缺乏足够的患者经验数据来确定这一点。我们对本机构在 7 年期间接受急性术后硬膜外镇痛和每日 3 次肝素治疗的 3705 例患者的脊柱硬膜外血肿发生率进行了回顾性分析。未报告脊柱硬膜外血肿病例（95%CI，0-0.0009952）。
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