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通过消除感染性颌部病变及臭氧疗法使侵袭性自身免疫性疾病(皮肌炎)缓解:综述与病例报告

Remission of aggressive autoimmune disease (dermatomyositis) with removal of infective jaw pathology and ozone therapy: review and case report.

作者信息

Rowen Robert Jay

机构信息

Private Medical Practice, 2200 County Center Dr. Ste C, Santa Rosa, CA, 95403, USA.

出版信息

Auto Immun Highlights. 2018 Jun 30;9(1):7. doi: 10.1007/s13317-018-0107-z.

DOI:10.1007/s13317-018-0107-z
PMID:29959639
原文链接:https://pmc.ncbi.nlm.nih.gov/articles/PMC6026108/
Abstract

INTRODUCTION

This case uniquely reports a connection between endodontically infected teeth and systemic disease, and additionally presents ozone therapy as a unique therapy and immune system modulator. It is the world's first such reported case and the treatment holds invaluable lessons in assessing the "unknown" causes of autoimmunity and inflammation. Additionally, it presents ozone therapy as a most needed unique, non-toxic and powerful anti-infective agent, anti-inflammatory and immune modulator.

CASE PRESENTATION

The patient was a Mexican male field laborer, age 48 years, in inflammatory crisis with a confirmed case of dermatomyositis. He had received massive prednisone, and powerful immune suppressing drugs just to function, while disease still raged. I encountered him in the field in June 2012 with severe muscle pain, weakness, and diffuse generalized skin rash, essentially unable to do his work. Creatine kinase peaked at 9293 U/L. History and physical examination findings caused suspicion of subclinical infections in endodontically treated teeth. This impression was confirmed in subsequent dental evaluation. He fully recovered after dental infections were confirmed and surgically removed, while receiving ozone therapy until all symptoms and laboratory abnormalities normalized.

CONCLUSION

Dental focus of occult infection may be a prime cause/trigger of autoimmune disorders and inflammatory disorders, requiring surgical intervention to remove. Ozone therapy, little known in conventional medicine, has been shown in the literature and in this case to be a powerful and safe immune modulator and anti-infective agent. This case has significant relevance across the entire spectrum of both medical and dental practice. It also emphasizes the need for individualized assessment and treatment rather than symptomatic pharmacological approaches treating a "disease" rather than the patient. Subclinical dental infection and ozone therapy are reviewed.

摘要

引言

本病例独特地报告了牙髓感染牙齿与全身性疾病之间的联系,并将臭氧疗法作为一种独特的治疗方法和免疫系统调节剂进行了介绍。这是世界上首例此类报告病例,该治疗为评估自身免疫和炎症的“未知”病因提供了宝贵经验。此外,它将臭氧疗法展现为一种极为需要的独特、无毒且强大的抗感染剂、抗炎剂和免疫调节剂。

病例介绍

患者为一名48岁的墨西哥男性田间劳动者,处于炎症危机中,确诊为皮肌炎。他仅靠服用大量泼尼松和强效免疫抑制药物来维持身体机能,然而疾病仍在肆虐。2012年6月,我在田间遇到他时,他肌肉剧痛、虚弱无力,全身弥漫性皮疹,基本无法工作。肌酸激酶峰值达到9293 U/L。病史和体格检查结果引发了对牙髓治疗牙齿中存在亚临床感染的怀疑。后续牙科评估证实了这一印象。在确认并手术清除牙齿感染的同时接受臭氧疗法后,他完全康复,直至所有症状和实验室异常指标恢复正常。

结论

隐匿性感染的牙齿病灶可能是自身免疫性疾病和炎症性疾病的主要病因/触发因素,需要通过手术干预予以清除。臭氧疗法在传统医学中鲜为人知,但文献及本病例均表明它是一种强大且安全的免疫调节剂和抗感染剂。该病例在整个医学和牙科实践领域都具有重要意义。它还强调了需要进行个体化评估和治疗,而非采用对症药物治疗“疾病”而非患者本身。本文对亚临床牙齿感染和臭氧疗法进行了综述。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/6cf31bf00118/13317_2018_107_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/f4e7a07f6ef9/13317_2018_107_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/4c0618bc0041/13317_2018_107_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/871039871dc1/13317_2018_107_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/29e2f5af49de/13317_2018_107_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/3a19084a5970/13317_2018_107_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/6cf31bf00118/13317_2018_107_Fig6_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/f4e7a07f6ef9/13317_2018_107_Fig1_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/4c0618bc0041/13317_2018_107_Fig2_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/871039871dc1/13317_2018_107_Fig3_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/29e2f5af49de/13317_2018_107_Fig4_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/3a19084a5970/13317_2018_107_Fig5_HTML.jpg
https://cdn.ncbi.nlm.nih.gov/pmc/blobs/9f9e/6026108/6cf31bf00118/13317_2018_107_Fig6_HTML.jpg

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