Elshazzly Mohamed, Bashjawish Fuad, Shahid Muhammad A, Marrero Dana A, Horowitz Joel
Campbell University School of Osteopathic Medicine, Lillington, NC, USA.
Department of Internal Medicine, Cape Fear Valley Hospital, Fayetteville, NC, USA.
Am J Case Rep. 2018 Jul 2;19:773-777. doi: 10.12659/AJCR.909545.
BACKGROUND Crohn's disease (CD) is an inflammatory bowel disease affecting approximately 1 in 3000 people in the United States. Since the inflammation of CD is transmural, patients are at risk for fistula and abscess formation. Retroperitoneal abscesses are one type of which physicians must be aware. CASE REPORT We present the case of a 29-year-old woman with CD who complained of right hip and flank pain that began when she was 6-months pregnant. After delivery, she continued to complain of severe right flank pain and was admitted to the hospital 1 month later. CT scan imaging revealed a complicated retroperitoneal and right flank abscess, possibly due to a colonic intramural fistula. She developed severe acute necrotizing soft-tissue infection requiring 13 days of intensive care. She required debridement of the necrotizing infection of the right flank, drainage of the abscess, and washout for intraperitoneal sepsis. The patient tolerated the procedures well and was discharged 1 month later. CONCLUSIONS Given that the clinical manifestation of retroperitoneal fistula with abscess is insidious and its formation is less common than intraperitoneal abscesses, we hope healthcare providers learn from this case to avoid morbidity and mortality. When presented with a pregnant CD patient complaining of nonspecific abdominal symptoms, providers should consider fistulization and/or abscess formation. The option to evaluate pregnant patients using noninvasive methods, such as ultrasound or low-dose CT scan, can decrease radiation exposure to the fetus and prevent delays in diagnosis and treatment.
克罗恩病(CD)是一种炎症性肠病,在美国约每3000人中就有1人受其影响。由于CD的炎症是透壁性的,患者有发生瘘管和脓肿形成的风险。腹膜后脓肿是医生必须知晓的其中一种类型。
我们报告一例29岁患有CD的女性病例,她在怀孕6个月时开始出现右髋部和侧腹疼痛。分娩后,她继续诉说严重的右侧腹疼痛,并在1个月后入院。CT扫描成像显示一个复杂的腹膜后和右侧腹脓肿,可能是由于结肠壁内瘘所致。她发展为严重的急性坏死性软组织感染,需要13天的重症监护。她需要对右侧腹的坏死感染进行清创、脓肿引流以及对腹腔脓毒症进行冲洗。患者对这些操作耐受良好,并在1个月后出院。
鉴于腹膜后瘘合并脓肿的临床表现隐匿,且其形成比腹腔脓肿少见,我们希望医疗服务提供者能从该病例中吸取教训,以避免发病和死亡。当面对一名怀孕的CD患者诉说非特异性腹部症状时,医疗服务提供者应考虑瘘管形成和/或脓肿形成。使用超声或低剂量CT扫描等非侵入性方法评估怀孕患者的选择,可以减少对胎儿的辐射暴露,并防止诊断和治疗的延迟。