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使用高效液相色谱-电喷雾电离-串联质谱法(HPLC-ESI-MS/MS)分析废水中的非法药物。

Analysis of Illicit Drugs in Wastewater Using High-Performance Liquid Chromatography-Electrospray Ionization-Tandem Mass Spectrometry (HPLC-ESI-MS/MS).

作者信息

Foppe Katelyn S, Subedi Bikram

机构信息

Department of Chemistry, Murray State University, Murray, KY, USA.

出版信息

Methods Mol Biol. 2018;1810:183-191. doi: 10.1007/978-1-4939-8579-1_16.

DOI:10.1007/978-1-4939-8579-1_16
PMID:29974428
Abstract

Consumption of illicit drugs is considered to be a global socioeconomic burden of adverse ecological and public health. Proper identification and quantification of trace level residues of illicit drugs in wastewater allow for an estimation of drug usage in a community, the amount of drug discharge into the environment, and the overall fate of drugs in the environment. This chapter provides a procedural detail of the determination of select illicit drugs and their metabolites in wastewater, suspended particulate matter, and sewage sludge using high-performance liquid chromatography-electrospray ionization-tandem mass spectrometry.

摘要

非法药物的消费被认为是一种对生态和公众健康产生不利影响的全球社会经济负担。对废水中非法药物痕量残留进行恰当的识别和定量,有助于估算社区中的药物使用情况、排入环境的药物量以及药物在环境中的总体归宿。本章详细介绍了使用高效液相色谱-电喷雾电离-串联质谱法测定废水中、悬浮颗粒物和污水污泥中选定非法药物及其代谢物的程序。

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