Reddy Radhika Z, Carter Yvonne M, Hsia David W
VA Long Beach Medical Center, Department of Medicine, Division of Pulmonary and Critical Care Medicine, USA1https://www.longbeach.va.gov/.
Sinai Hospital of Baltimore, Department of Surgery, Division of Thoracic Surgery, USA2http://www.lifebridgehealth.org/Sinai/SinaiDivisionofThoracicSurgery.aspx.
Respir Med Case Rep. 2018 May 3;24:113-116. doi: 10.1016/j.rmcr.2018.05.003. eCollection 2018.
Pulmonary inflammatory pseudotumor (PIP) is a rare benign tumor that represents less than one percent of all tumors found in the lungs. Despite the benign etiology, PIP can cause significant clinical problems due to its growth rate and potential to compromise adjacent pulmonary and thoracic structures. Complete surgical resection is the preferred therapy for PIP to prevent recurrence, however, this is not possible in some patients due to the size or location of the tumor. We present the case of an 18 year-old male presenting with PIP in the proximal left mainstem bronchus causing complete left lung collapse. Surgical resection was not possible due to tumor location, and therefore the patient was treated with corticosteroids with marked response. Corticosteroid use has for PIP has been described in few other situations, and this case demonstrates the potential for this therapeutic option in patients with PIP who have a contraindication to surgical resection.
肺炎性假瘤(PIP)是一种罕见的良性肿瘤,在所有肺部肿瘤中所占比例不到1%。尽管病因良性,但由于其生长速度以及可能累及相邻肺部和胸部结构,PIP可导致严重的临床问题。完整的手术切除是预防PIP复发的首选治疗方法,然而,由于肿瘤的大小或位置,部分患者无法进行手术。我们报告一例18岁男性患者,其左主支气管近端出现PIP,导致左肺完全塌陷。由于肿瘤位置原因无法进行手术切除,因此该患者接受了皮质类固醇治疗,反应显著。皮质类固醇用于PIP的情况在其他少数病例中也有描述,本病例表明,对于有手术切除禁忌证的PIP患者,这种治疗选择具有潜力。