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生命重于肢体:主动脉复苏性血管内球囊阻断(REBOA)情况下的下肢缺血

Life over Limb: Lower Extremity Ischemia in the Setting of Resuscitative Endovascular Balloon Occlusion of the Aorta (REBOA).

作者信息

Wasicek Philip J, Teeter William A, Yang Shiming, Hu Peter, Hoehn Melanie R, Stein Deborah M, Scalea Thomas M, Brenner Megan L

出版信息

Am Surg. 2018 Jun 1;84(6):971-977.

Abstract

Resuscitative endovascular balloon occlusion of the aorta (REBOA) is a temporizing maneuver used to decrease hemorrhage, and thus perfusion, below the level of aortic occlusion (AO). We sought to investigate lower extremity ischemia in patients who received REBOA. Between February 2013 and September 2016 patients at a tertiary center that received REBOA and survived more than six hours were enrolled. Thirty-one patients were identified, the mean ISS was 40 ± 14 and inhospital mortality was 39 per cent. Twenty received REBOA in zone 1 (distal thoracic aorta). Three (15%) developed lower extremity compartment syndrome (LECS) after zone 1 REBOA. Injury of iliofemoral arteries and veins was each associated with calf fasciotomies (both P = 0.005). A longer duration of AO at zone 1 was associated with calf and thigh fasciotomy (P = 0.046 and P = 0.048, respectively). Iliofemoral arterial injury was associated with thigh fasciotomy (P = 0.04). Eleven patients received REBOA in zone 3 (distal abdominal aorta). Five (45%) patients underwent fasciotomy; four (36%) due to LECS. Femoral arterial injury was associated with calf fasciotomies (P = 0.02). There was no association with sheath size or laterality and need for fasciotomy. Neither groin access for REBOA or AO solely caused limb loss or LECS. The contribution to distal ischemia by REBOA remains unclear in patients with lower extremity injury.

摘要

主动脉内复苏球囊阻断术(REBOA)是一种用于减少出血从而降低主动脉阻断(AO)水平以下灌注的临时措施。我们旨在调查接受REBOA治疗的患者的下肢缺血情况。在2013年2月至2016年9月期间,一家三级中心接受REBOA且存活超过6小时的患者被纳入研究。共确定了31例患者,平均损伤严重度评分(ISS)为40±14,住院死亡率为39%。20例患者在1区(胸主动脉远端)接受了REBOA。其中3例(15%)在1区REBOA后发生了下肢筋膜室综合征(LECS)。髂股动脉和静脉损伤均与小腿筋膜切开术相关(P值均为0.005)。1区较长的AO持续时间与小腿和大腿筋膜切开术相关(分别为P = 0.046和P = 0.048)。髂股动脉损伤与大腿筋膜切开术相关(P = 0.04)。11例患者在3区(腹主动脉远端)接受了REBOA。5例(45%)患者接受了筋膜切开术;4例(36%)是由于LECS。股动脉损伤与小腿筋膜切开术相关(P = 0.02)。鞘管大小或左右侧别与筋膜切开术的需求无关。REBOA或AO的腹股沟入路单独均未导致肢体丧失或LECS。对于下肢受伤的患者,REBOA对远端缺血的影响仍不清楚。

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