Department of Psychology, School of Business, Reykjavík University, 101 Reykjavík, Iceland.
J Public Health (Oxf). 2019 Jun 1;41(2):422-426. doi: 10.1093/pubmed/fdy116.
Public financing to incentivise private sector innovation in antimicrobial pharmaceuticals is believed by many to be necessary to defeat growing threats from antimicrobial resistance. Large cash incentives from the public sector are said to be essential to stimulate 'normal' market forces capable of unleashing much-needed innovation. However, there is little evidence to suggest that lack of innovation in drug development is peculiar to antimicrobials or that current deficits in the supply of antimicrobials is due to unique inefficiencies in the antimicrobial market. Neither the history of drug development in general nor of antimicrobial innovation in particular supports economic interventions intended to stimulate private sector supply of new antimicrobials. On the contrary, public underwriting of the private sector, which by definition is compelled to prioritise profit, risks dire consequences for future global health.
许多人认为,需要公共资金来激励私营部门对抗生素制药的创新,以应对日益严重的抗微生物药物耐药性威胁。据称,来自公共部门的大量现金激励对于刺激能够释放出急需的创新的“正常”市场力量至关重要。然而,几乎没有证据表明药物开发方面的创新不足是抗菌药物所特有的,或者目前抗菌药物供应不足是由于抗菌药物市场存在独特的效率低下所致。无论是一般的药物开发历史还是特定的抗菌药物创新历史都不支持旨在刺激私营部门供应新抗生素的经济干预措施。相反,公共部门对私营部门的承保,根据定义,必须优先考虑利润,这可能会给未来的全球健康带来可怕的后果。