Jung Na-Yeon, Lee Jae-Hyeok, Lee Young Min, Shin Jin-Hong, Shin Myung-Jun, Lee Myung Jun, Pak Kyoungjune, Hwang Chungsu, Ahn Jae Woo, Sung Suk, Choi Kyung-Un, Huh Gi Yeong, Kim Eun-Joo
a Department of Neurology, Research Institute for Convergence of Biomedical Science and Technology , Pusan National University Yangsan Hospital , Yangsan , South Korea.
b Department of Psychiatry , Pusan National University Hospital , Busan , South Korea.
Neurocase. 2018 Jun;24(3):145-150. doi: 10.1080/13554794.2018.1494290. Epub 2018 Jul 10.
Corticobasal syndrome (CBS) is a typical phenotype of corticobasal degeneration (CBD). However, autopsy series have shown that many CBS cases emerge from various types of non-CBD pathology. We report a 73-year-old Korean man who was clinically diagnosed with CBS whose underlying pathology was Alzheimer's disease (AD) at autopsy (CBS-AD). This case suggests that early developing memory impairment and myoclonus, severe temporoparietal atrophy, and visual hallucinations may support a more specific prediction of CBS-AD.
皮质基底节综合征（CBS）是皮质基底节变性（CBD）的典型表型。然而，尸检系列研究表明，许多CBS病例源于各种类型的非CBD病理学。我们报告了一名73岁的韩国男性，临床诊断为CBS，尸检时发现其潜在病理为阿尔茨海默病（AD）（CBS-AD）。该病例表明，早期出现的记忆障碍和肌阵挛、严重的颞顶叶萎缩以及视幻觉可能有助于对CBS-AD进行更具体的预测。
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