Departments of Psychiatry, University of Florida, 100 S. Newell Drive, L-4100, Gainesville, FL 32601, United States.
Department of Neurology, University of California, San Francisco, 675 Nelson Rising Lane, Suite 190, San Francisco, CA 94158, United States.
Psychiatry Res. 2018 Oct;268:157-164. doi: 10.1016/j.psychres.2018.07.012. Epub 2018 Jul 10.
Hoarding disorder (HD) has been hypothesized to arise from deficits in error monitoring and abnormalities in emotional processing, but the relationship between error monitoring and emotional processing has not been examined. We examined measures of self-report, as well as behavioral, physiological, and facial responses to errors during a Stop-Change Task. 25 participants with HD and 32 healthy controls (HC) were recruited. Participants reported on number of errors committed and pre/post emotional response to errors. Skin conductance response (SCR) during correct and error commission trials was examined. Facial expression during task performance was coded for self-conscious and negative emotions. HD and HC participants had significantly different error rates but comparable error correction and post-error slowing. SCR was significantly lower for HD during error commission than for HC. During error trials, HD participants showed a significant deficit in displays of self-conscious emotions compared to HC. Self-reported emotions were increased in HD, with more negative and self-conscious emotion reported than was reported for HC participants. These findings suggest that hypoactive emotional responding at a physiological level may play a role in how errors are processed in individuals with HD.
囤积症（HD）被假设为源于错误监测缺陷和情绪处理异常，但错误监测和情绪处理之间的关系尚未得到检验。我们检查了自我报告的措施，以及在停止变化任务期间对错误的行为、生理和面部反应。招募了 25 名 HD 患者和 32 名健康对照组（HC）。参与者报告了犯错误的次数以及对错误的前后情绪反应。在正确和错误提交试验期间检查了皮肤电导反应（SCR）。对任务表现期间的面部表情进行了自我意识和负面情绪的编码。HD 和 HC 参与者的错误率有显著差异，但错误纠正和错误后减速相当。与 HC 相比，HD 在错误提交期间的 SCR 明显较低。在错误试验中，与 HC 相比，HD 参与者在自我意识情绪的表现上存在明显缺陷。与 HC 参与者相比，HD 参与者报告的自我报告情绪增加，报告的负面和自我意识情绪更多。这些发现表明，在生理水平上，情绪反应不足可能在 HD 患者的错误处理中起作用。
