O2 consumption of the amphibian cornea: relationship to Na+ and Cl- and the presence of drugs.

Thirty percent of the O2 consumption of the amphibian cornea was Na-dependent. Ouabain, in the presence but not the absence of this cation, inhibits O2 uptake by about 30 patient. In contrast, neither the presence of Cl- nor drugs which stimulate (adrenaline, theophylline) or inhibit (furosemide, thiocyanate) active transport of this anion had detectable effects on O2 consumption.