通过葡萄糖、时间和癫痫发作起始侧别进行的连续监测设备及癫痫发作模式
Continuous monitoring devices and seizure patterns by glucose, time and lateralized seizure onset.
作者信息
Kinnear Katie M, Warner Nicole M, Haltiner Alan M, Doherty Michael J
机构信息
Swedish Epilepsy Center, Seattle, WA, USA.
出版信息
Epilepsy Behav Case Rep. 2018 Mar 21;10:65-70. doi: 10.1016/j.ebcr.2018.03.001. eCollection 2018.
OBJECTIVES
To investigate if glucose levels influence seizure patterns.
MATERIALS AND METHODS
In a patient with RNS/NeuroPace implanted bi-temporally and type 1 diabetes mellitus, seizure event times and onset locations were matched to continuous tissue glucose.
RESULTS
Left focal seizure (LFS, n = 22) glucoses averaged 169 mg/dL, while right focal seizure (RFS, n = 23) glucoses averaged 131 mg/dL (p = 0.03). LFS occurred at mean time 17:02 while RFS occurred at 04:23. LFS spread to the contralateral side (n = 19) more than RFS (n = 2).
CONCLUSION
Seizure onset laterality and spread vary with glucose and time of seizure.
目的
研究血糖水平是否会影响癫痫发作模式。
材料与方法
在一名双侧植入RNS/NeuroPace且患有1型糖尿病的患者中，将癫痫发作事件时间和发作起始部位与连续的组织葡萄糖水平进行匹配。
结果
左侧局灶性癫痫（LFS，n = 22）的血糖平均为169mg/dL，而右侧局灶性癫痫（RFS，n = 23）的血糖平均为131mg/dL（p = 0.03）。LFS平均发作时间为17:02，而RFS发作时间为04:23。LFS扩散至对侧（n = 19）的情况比RFS（n = 2）更多。
结论
癫痫发作的起始侧别和扩散情况随血糖水平及发作时间而变化。
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