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产后抑郁症状的潜在轨迹分类:一项基于区域人群的纵向研究。

Latent trajectory classes of postpartum depressive symptoms: A regional population-based longitudinal study.

机构信息

Department for Infant Mental Health, Regional Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway.

Department for Infant Mental Health, Regional Center for Child and Adolescent Mental Health, Eastern and Southern Norway, Oslo, Norway.

出版信息

J Affect Disord. 2018 Dec 1;241:29-36. doi: 10.1016/j.jad.2018.07.081. Epub 2018 Aug 1.

Abstract

PURPOSE

This study aimed to (a) assess trajectories of women's depressive symptoms during the first year postpartum to (b) identify potential unobserved classes of women as defined by their trajectories, (c) identify antepartum and early postpartum risk factors associated with trajectory classes, and (d) examine the association between trajectory classes and counselling during the postpartum period.

METHODS

Data on depressive symptoms, using the Edinburgh Postnatal Depression Scale (EPDS), were collected from 1374 women across nine Norwegian well-baby clinics at 1.5, 4, 6, and 12 months postpartum. Well-baby clinics offer universal, free services to all families living in the municipality. Thus, there were no specific exclusion criteria for this study. All clinics had implemented the Edinburgh-method which combines screening for PPD, using the EPDS, with supportive counselling.

RESULTS

Analyses showed that depressive symptoms decreased initially, followed by a flattening in symptoms at 6 months. Mixture analyses, however, identified two classes of women with distinct trajectories; (1) a low-risk (n = 1249, 91%) and (2) a high-risk group (n = 119, 9%). Complications after birth, elevated prenatal depressive symptoms, previous or current mental illness, and gestational week, predicted trajectory class membership. Women in the high-risk group were more likely to receive counselling than low-risk women.

LIMITATIONS

Women had higher educational level than the general population and one of the municipalities did not have a 12-months routine consultation.

CONCLUSION

Findings suggest heterogeneity among women in their depressive symptoms during the first year postpartum with a distinct set of risk factors associated with high-risk women. This has implications for the prevention and follow-up of women during pregnancy and the first year after childbirth.

摘要

目的

本研究旨在:(a)评估女性产后第一年抑郁症状的轨迹;(b)根据轨迹确定潜在的未观察到的女性类别;(c)确定与轨迹类别相关的产前和产后早期风险因素;(d)探讨轨迹类别与产后咨询之间的关联。

方法

使用爱丁堡产后抑郁量表(EPDS),在 9 家挪威婴儿诊所对 1374 名女性在产后 1.5、4、6 和 12 个月时进行抑郁症状的调查。婴儿诊所为所有居住在该城市的家庭提供普遍、免费的服务。因此,本研究没有具体的排除标准。所有诊所都实施了爱丁堡方法,该方法将 PPD 的筛查与 EPDS 相结合,并提供支持性咨询。

结果

分析显示,抑郁症状最初下降,随后在 6 个月时症状趋于平稳。然而,混合分析确定了两组具有不同轨迹的女性:(1)低风险组(n=1249,91%)和(2)高风险组(n=119,9%)。产后并发症、产前抑郁症状升高、既往或当前精神疾病以及妊娠周数预测了轨迹类别。高风险组的女性比低风险女性更有可能接受咨询。

局限性

与一般人群相比,这些女性的受教育程度较高,且其中一个城镇没有 12 个月的常规咨询。

结论

研究结果表明,产后第一年女性的抑郁症状存在异质性,与高风险女性相关的风险因素也各不相同。这对妊娠和产后第一年期间女性的预防和随访具有重要意义。

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