Schnabel K, Berberich W, Scharding B, Niewald M, Tkocz H J, Dietz R
Strahlenther Onkol. 1986 May;162(5):285-90.
Until 1983, more than 300 astrocytomas of degree III and IV have been irradiated all over the world with new types of radiation such as neutrons, protons, alpha particles, heavy ions, and pions. Up to now a therapeutic progress could not be achieved. Radiobiologic experimentations suggest that the dense ionisation is unfavorable in the irradiation of malignant cerebral tumors. The clinical radiotherapy research with protons should therefore be intensified and hyperfractionation should be critically reviewed.
直到1983年,世界各地已用中子、质子、α粒子、重离子和π介子等新型辐射对300多例III级和IV级星形细胞瘤进行了照射。到目前为止,尚未取得治疗进展。放射生物学实验表明,密集电离对恶性脑肿瘤的照射不利。因此,应加强质子临床放射治疗研究,并对超分割放疗进行严格审查。