and are essential for the resistance of against fungal pathogen .

Pleiotropic drug resistance (PDR) transporters are widely distributed membrane proteins catalyzing the export or import of a diverse array of molecules, and are involved in many plant responses to biotic and abiotic stresses. However, it is unclear whether PDRs are involved in resistance to the necrotic fungal pathogen . In this study, transcriptional levels of both and were highly induced in leaves after inoculation. Interestingly, silencing or individually had little effect on resistance to ; however, when both genes were co-silenced plants became highly susceptible to the fungus, which was associated with elevated JA and ethylene responses. Neither nor was significantly elicited by exogenous treatment with methyl jasmonate (MeJA), whereas both were highly induced by ethylene. The elicitation levels of both genes by were significantly reduced in plants with impaired JA or ethylene signaling pathways. Thus, we conclude that both and function redundantly to confer resistance against . in , and the elicitation of the transcripts of both genes by the fungus is partially dependent on ethylene and jasmonate signaling.