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遗传连锁

Genetic linkage.

作者信息

Yates J R, Connor J M

出版信息

Br J Hosp Med. 1986 Aug;36(2):133-6.

PMID:3017485
Abstract

Not all doctors would understand the statement "linkage is now established between a DNA marker and the locus for adult polycystic kidney disease at a recombination fraction of 5%". Yet over the next few years increasing numbers of DNA markers linked to single-gene disorders will become available and clinicians will need to identify patients who could benefit from this knowledge.

摘要

并非所有医生都能理解“现已确定一个DNA标记与成年多囊肾病位点之间存在连锁关系,重组率为5%”这句话。然而,在未来几年,与单基因疾病相关的DNA标记将会越来越多,临床医生将需要识别那些能从这一知识中受益的患者。

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