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Squamous cell carcinoma transformation from adenocarcinoma as an acquired resistance after the EGFR TKI therapy in (EGFR-mutated) non-small cell lung cancer.

作者信息

Shinohara Shinji, Ichiki Yoshinobu, Fukuichi Yukiko, Honda Yohei, Kanayama Masatoshi, Taira Akihiro, Nabe Yusuke, Kuwata Taiji, Takenaka Masaru, Oka Soichi, Chikaishi Yasuhiro, Hirai Ayako, Imanishi Naoko, Kuroda Koji, Yoneda Kazue, Noguchi Hirotsugu, Tanaka Fumihiro

机构信息

Second Department of Surgery, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

Department of Pathology and Cell Biology, School of Medicine, University of Occupational and Environmental Health, Kitakyushu, Japan.

出版信息

J Thorac Dis. 2018 Jul;10(7):E526-E531. doi: 10.21037/jtd.2018.06.83.

Abstract
摘要

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本文引用的文献

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Histopathological transformation to small-cell lung carcinoma in non-small cell lung carcinoma tumors.
Transl Lung Cancer Res. 2016 Aug;5(4):401-12. doi: 10.21037/tlcr.2016.07.10.
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Association Between Plasma Genotyping and Outcomes of Treatment With Osimertinib (AZD9291) in Advanced Non-Small-Cell Lung Cancer.
J Clin Oncol. 2016 Oct 1;34(28):3375-82. doi: 10.1200/JCO.2016.66.7162. Epub 2016 Jun 27.
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Squamous Cell Carcinoma "Transformation" Concurrent with Secondary T790M Mutation in Resistant EGFR-Mutated Adenocarcinomas.
J Thorac Oncol. 2016 Apr;11(4):e49-51. doi: 10.1016/j.jtho.2015.12.096. Epub 2015 Dec 30.
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Phase III study of afatinib or cisplatin plus pemetrexed in patients with metastatic lung adenocarcinoma with EGFR mutations.
J Clin Oncol. 2013 Sep 20;31(27):3327-34. doi: 10.1200/JCO.2012.44.2806. Epub 2013 Jul 1.
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Genotypic and histological evolution of lung cancers acquiring resistance to EGFR inhibitors.
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