Noh Sang Jae, Lee Ho
Department of Forensic Medicine, Chonbuk National University Medical School, Research Institute of Clinical Medicine of Chonbuk National University-Biomedical Research Institute of Chonbuk National University Hospital and Research Institute for Endocrine Sciences , Jeonju-si, Korea.
High Alt Med Biol. 2018 Sep;19(3):288-290. doi: 10.1089/ham.2017.0137. Epub 2018 Sep 4.
Noh, Sang Jae and Ho Lee. Rapidly progressing fatal high-altitude illness in a patient with hyperthyroidism. High Alt Med Biol. 19:288-290, 2018.-High-altitude illness (HAI) refers to a broad spectrum of diseases ranging from acute mountain sickness to high-altitude cerebral and pulmonary edema that are induced by high-altitude hypoxic stress. In this study, we present a case of a rapidly progressing fatal HAI (high-altitude cerebral edema and pulmonary edema) in a patient with hyperthyroidism. The victim is a 20-year-old female being treated for Graves' disease, who died after visiting a high-altitude region for travel. The autopsy examination showed cerebral and pulmonary edema, and right ventricular enlargement. A postmortem thyroid function test revealed thyrotoxic status; thyrotoxicosis may have contributed to the rapid progression of the HAI.
诺，桑杰和何李。一名甲状腺功能亢进患者快速进展的致命高原病。《高原医学与生物学》。2018年第19卷：288 - 290页。 - 高原病（HAI）指的是一系列由高原低氧应激诱发的疾病，范围从急性高山病到高原脑水肿和肺水肿。在本研究中，我们报告了一例甲状腺功能亢进患者快速进展的致命高原病（高原脑水肿和肺水肿）病例。受害者是一名20岁患有格雷夫斯病正在接受治疗的女性，她在前往高海拔地区旅行后死亡。尸检显示有脑水肿、肺水肿以及右心室增大。死后甲状腺功能测试显示甲状腺毒症状态；甲状腺毒症可能促使了高原病的快速进展。
