Naughton John P, Lee Andrew Y, Ramos Eric, Wootton David, Stupak Howard D
1 Department of Otorhinolaryngology-Head & Neck Surgery, Albert Einstein College of Medicine, Bronx, New York, USA.
2 Department of Mechanical Engineering, The Cooper Union, New York, New York, USA.
Ann Otol Rhinol Laryngol. 2018 Nov;127(11):745-753. doi: 10.1177/0003489418791597. Epub 2018 Sep 7.
The relative importance of the nasal valve relative to the remainder of the nasal airway remains unknown. The goal of this article was to objectively measure the shape of the nasal inlet and its effect on downstream airflow and nasal cavity volume using a physical model and a physiologic flow model.
A patient who had isolated nasal valve surgery and had pre- and postoperative computed tomography scans available for analysis was studied. Nasal inlet shape measurements, computational fluid dynamics, and nasal volume analysis were performed using the computed tomography data. In addition, a physical model was used to determine the effect of nasal obstruction on downstream soft tissue.
The postoperative shape of the nasal inlet was improved in terms of length and degree of tortuosity. Whereas the operated-on region at the nasal inlet showed an only 25% increase in cross-sectional area postoperatively, downstream nonoperated sites in the nasal cavity revealed increases in area ranging from 33% to 51%. Computational fluid dynamics analysis showed that airway resistance decreased by 42%, and pressure drop was reduced by 43%. Intraluminal mucosal expansion was found with nasal obstruction in the physical model.
By decreasing the degree of bending and length at the nasal valve, inspiratory downstream nonoperated sites of the nasal cavity showed improvement in volume and airflow, suggesting that the nasal valve could play an oversized role in modulating the aerodynamics of the airway. This was confirmed with the physical model of nasal obstruction on downstream mucosa.
鼻瓣相对于鼻气道其余部分的相对重要性尚不清楚。本文的目的是使用物理模型和生理流动模型客观测量鼻入口的形状及其对下游气流和鼻腔容积的影响。
对一名接受过单纯鼻瓣手术且有术前和术后计算机断层扫描可供分析的患者进行研究。使用计算机断层扫描数据进行鼻入口形状测量、计算流体动力学分析和鼻腔容积分析。此外,使用物理模型确定鼻阻塞对下游软组织的影响。
鼻入口的术后形状在长度和弯曲程度方面得到改善。尽管鼻入口处的手术区域术后横截面积仅增加了25%,但鼻腔内未手术的下游部位面积增加了33%至51%。计算流体动力学分析表明气道阻力降低了42%,压降降低了43%。在物理模型中发现鼻阻塞时管腔内黏膜扩张。
通过降低鼻瓣处的弯曲程度和长度,鼻腔吸气下游未手术部位的容积和气流得到改善,这表明鼻瓣在调节气道空气动力学方面可能发挥着过大的作用。这在鼻阻塞对下游黏膜的物理模型中得到了证实。