Onishi Takehisa, Sekito Sho, Terabe Takeshi, Shibahara Takuji
Department of Urology, Ise Red Cross Hospital, Ise, Japan
Department of Urology, Ise Red Cross Hospital, Ise, Japan.
Anticancer Res. 2018 Sep;38(9):5525-5530. doi: 10.21873/anticanres.12887.
BACKGROUND/AIM: The aim of the study was to identify the reliable predictor for early recovery of urinary continence (UC) after non-nerve-sparing laparoscopic radical prostatectomy (NNS-LRP) according to the findings of pre- and postoperative imaging.
A retrospective analysis of 215 patients who underwent NNS-LRP was carried out. Early recovery of UC was defined as using no pads or one security pad per day within 3 months. Preoperative membranous urethral length (MUL) measured on MRI and postoperative bladder neck angle (BNA) identified by cystography were analyzed to evaluate the relationship with recovery of UC. Patients were divided into three groups based on MUL and BNA (Group A: MUL ≥12.1 mm and BNA ≥103°, Group B: either MUL ≥12.1 mm or BNA ≥103°, Group C: MUL <12.1 mm and BNA <103°.
Early recovery rates were 80.3% in patients with MUL ≥12.1 mm, 37.5% in patients with MLU<12.1 (p<0.001), and 77.8% in patients with BNA ≥103°, 50% in patients with BNA <103°(p<0.001). In the combination of the two parameters, early recovery rates were 90.4%, 58%, and 36.1% in group A, B and C respectively (p<0.001). Kaplan-Meier curve of the time to recovery of UC showed significant differences among the three groups (log rank test: p<0.001).
A combination of preoperative MUL and postoperative BNA was the reliable predictor of recovery of UC after NNS-LRP. Longer MUL with wider BNA is significantly and positively associated with an early recovery of UC.
背景/目的:本研究旨在根据术前和术后影像学检查结果,确定非保留神经腹腔镜根治性前列腺切除术(NNS-LRP)后尿失禁(UC)早期恢复的可靠预测指标。
对215例行NNS-LRP的患者进行回顾性分析。UC的早期恢复定义为术后3个月内无需使用尿垫或每天仅使用1个安全尿垫。分析术前MRI测量的膜部尿道长度(MUL)和术后膀胱造影确定的膀胱颈角度(BNA)与UC恢复的关系。根据MUL和BNA将患者分为三组(A组:MUL≥12.1mm且BNA≥103°;B组:MUL≥12.1mm或BNA≥103°;C组:MUL<12.1mm且BNA<103°)。
MUL≥12.1mm的患者早期恢复率为80.3%,MUL<12.1mm的患者为37.5%(p<0.001);BNA≥103°的患者早期恢复率为77.8%,BNA<103°的患者为50%(p<0.001)。在两个参数的组合中,A、B、C组的早期恢复率分别为90.4%、58%和36.1%(p<0.001)。UC恢复时间的Kaplan-Meier曲线显示三组之间存在显著差异(对数秩检验:p<0.001)。
术前MUL和术后BNA的组合是NNS-LRP后UC恢复的可靠预测指标。MUL较长且BNA较宽与UC的早期恢复显著正相关。