外用氨甲环酸治疗使用抗血小板药物患者的鼻出血
Topical tranexamic acid for the treatment of epistaxis in patients using antiplatelet agents.
作者信息
Sanderson Mark, Powell James, Lang Eddy
机构信息
*University of British Columbia,Vancouver,BC.
‡Emergency Medicine,Cumming School of Medicine,University of Calgary,Calgary,AB.
出版信息
CJEM. 2018 Sep;20(5):774-776. doi: 10.1017/cem.2018.422.
UNLABELLED
ABSTRACTClinical questionDoes the addition of topical tranexamic acid to anterior nasal packing decrease bleeding in patients with epistaxis who are taking antiplatelet medications?Article chosenZahed R, Jayazeri M, Naderi A, et al. Topical tranexamic acid compared with anterior nasal packing for treatment of epistaxis in patients taking antiplatelet drugs: randomized controlled trial. Acad Emerg Med 2018;25(3):261-6.
OBJECTIVES
The primary outcome of this randomized controlled trial was the percentage of patients whose epistaxis had stopped at 10 minutes from the time of intervention. Secondary outcomes included the frequency of epistaxis recurrence at both 24 hours and 7 days, emergency department length of stay, and patient satisfaction.
未标注
摘要
临床问题
对于正在服用抗血小板药物的鼻出血患者，在前鼻孔填塞时添加局部用氨甲环酸是否能减少出血？
所选文章
扎赫德R、贾亚泽里M、纳迪里A等。局部用氨甲环酸与前鼻孔填塞治疗服用抗血小板药物患者鼻出血的比较：随机对照试验。《学术急诊医学》2018年；25(3):261 - 266。
目的
这项随机对照试验的主要结局是干预后10分钟鼻出血停止的患者百分比。次要结局包括24小时和7天时鼻出血复发的频率、急诊科住院时间以及患者满意度。
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