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评论“用于浅表目标的准直质子铅笔束扫描:射程移位器和孔径顺序的影响”。

Comment on 'Collimated proton pencil-beam scanning for superficial targets: impact of the order of range shifter and aperture'.

机构信息

Centre for Proton Therapy, Paul Scherrer Institute, Villigen, Switzerland. Department of Physics, ETH Zürich, Zurich, Switzerland.

出版信息

Phys Med Biol. 2018 Oct 17;63(20):208001. doi: 10.1088/1361-6560/aae0e1.

Abstract

We read with interest the study by Bäumer et al (2018 Phys. Med. Biol. 63 085020), in particular that their conclusions are in contrast to those of our earlier paper (Winterhalter et al 2018 Phys. Med. Biol. 63 025022), namely that positioning the collimating aperture downstream of the range shifter leads to a superior penumbra. In contrast, we found sharper penumbras for the PSI scanning Gantry when the aperture is positioned upstream of the range shifter. We have run additional Monte Carlo simulations with components derived from the paper of Bäumer et al (2018 Phys. Med. Biol. 63 085020), but without modifying the beam description. As such, we obtain a relative penumbra reduction of 13% if the aperture is positioned downstream of the ranges shifter, which lies well within the measured/calculated penumbra reductions of Bäumer et al (2018 Phys. Med. Biol. 63 085020) of 17%/11%. The conclusions of Bäumer et al (2018 Phys. Med. Biol. 63 085020) and our previous work are therefore complementary, given the differences in the thicknesses of the beam modifying devices used in the two works. In addition, our analysis implies that initial beam characteristics are less important in determining the best order of components.

摘要

我们饶有兴趣地阅读了 Bäumer 等人(2018 年《物理医学与生物学》63085020)的研究,特别是他们的结论与我们早期的论文(Winterhalter 等人,2018 年《物理医学与生物学》63025022)相矛盾,即准直器的位置在射程移位器的下游会导致更好的半影。相比之下,当孔径位于射程移位器的上游时,我们发现 PSI 扫描龙门架的半影更锐利。我们使用 Bäumer 等人(2018 年《物理医学与生物学》63085020)论文中的组件进行了额外的蒙特卡罗模拟,但没有修改光束描述。因此,如果孔径位于射程移位器的下游,我们获得了相对半影减少 13%,这与 Bäumer 等人(2018 年《物理医学与生物学》63085020)测量/计算的半影减少 17%/11%非常吻合。鉴于这两篇论文中使用的光束修正设备的厚度存在差异,因此 Bäumer 等人(2018 年《物理医学与生物学》63085020)和我们之前的工作的结论是互补的。此外,我们的分析意味着初始光束特性在确定组件的最佳顺序方面不太重要。

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