法国里昂的α-1抗胰蛋白酶（Pi）表型：偏离哈迪-温伯格平衡
Alpha-I-antitrypsin (Pi) phenotypes in Lyon, France: departure from Hardy-Weinberg equilibrium.
作者信息
Arnaud P, Pandey J P, Fudenberg H H, Chapuis-Cellier C, Vittoz P, Creyssel R
出版信息
Clin Genet. 1977 Aug;12(2):77-9. doi: 10.1111/j.1399-0004.1977.tb00905.x.
Abstract
The validity of the Hardy-Weinberg equilibrium for Pi phenotypes was tested in a population of 1,653 randomly selected, healthy blood donors in Lyon, France. A significant departure from the equilibrium was found, with an excess of FF and SS homozygotes and a deficiency of FM heterozygotes.
摘要
在法国里昂随机挑选的1653名健康献血者群体中，对Pi表型的哈迪-温伯格平衡的有效性进行了检验。结果发现显著偏离平衡，FF和SS纯合子过多，而FM杂合子不足。
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