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真性红细胞增多症所致缺血性结肠炎:一例报告及文献复习

Ischemic colitis caused by polycythemia vera: A case report and literature review.

作者信息

Zhang Shasha, Lai Ruixue, Gao Xueqing, Zhao Yufei, Zhao Yue, Wu Jianhua, Guo Zhanjun

机构信息

Department of Rheumatology and Immunology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, P.R. China.

Department of Gastroenterology and Hepatology, The Fourth Hospital of Hebei Medical University, Shijiazhuang, Hebei 050011, P.R. China.

出版信息

Exp Ther Med. 2018 Oct;16(4):3663-3667. doi: 10.3892/etm.2018.6638. Epub 2018 Aug 22.

Abstract

Polycythemia vera (PV) is a chronic myeloproliferative disorder originating from hematopoietic stem cells and complicated by thrombosis and bleeding. This report describes a case of ischemic colitis (IC) caused by PV and includes a review of the relevant literature. The patient was a 59-year-old male with a history of PV who presented with abdominal pain and hematochezia. Colonoscopy and histopathological examination results indicated suspected ischemic bowel disease. Following experimental anticoagulant therapy for 7 days, the patient no longer experienced abdominal pain and hematochezia had resolved. Colonoscopy review showed no obvious anomalies 1 month later. These data demonstrated that PV is an uncommon cause of IC.

摘要

真性红细胞增多症(PV)是一种起源于造血干细胞的慢性骨髓增殖性疾病,可并发血栓形成和出血。本报告描述了一例由PV引起的缺血性结肠炎(IC)病例,并对相关文献进行了综述。该患者为一名59岁男性,有PV病史,表现为腹痛和便血。结肠镜检查和组织病理学检查结果提示疑似缺血性肠病。经过7天的试验性抗凝治疗后,患者不再腹痛,便血已消失。1个月后复查结肠镜检查未见明显异常。这些数据表明PV是IC的一种罕见病因。

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