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“必要性-关注框架”作为一种理解三种慢性疾病患者不遵医行为的方法,并应用多项式回归。

The 'Necessity-Concerns Framework' as a means of understanding non-adherence by applying polynomial regression in three chronic conditions.

机构信息

Medicines Use Research Group, Department of Clinical Pharmacology and Therapeutics, Faculty of Medicine and Surgery, University of Malta, Msida, Malta.

出版信息

Chronic Illn. 2020 Dec;16(4):253-265. doi: 10.1177/1742395318799847. Epub 2018 Sep 20.

Abstract

OBJECTIVE

The 'Necessity-Concerns Framework' is an important framework which can support healthcare professionals in targeting patients' medication beliefs and decisions on adherence. Our aim was to determine how the interdependence of 'necessity' and 'concerns' beliefs for medication adherence compares across three chronic conditions.

METHODS

Patients diagnosed with asthma, cardiovascular conditions or diabetes attending out-patient clinics completed a self-administered questionnaire. The questionnaire gathered information regarding demographics, medication adherence using the 'Tool for Adherence Behaviour Screening', presence of unused medication in households and medication beliefs using the 'Beliefs about Medicines Questionnaire-Specific'. Polynomial regression was applied to determine the multidimensional interdependence of 'necessity' and 'concerns' beliefs for adherence. -values ≤ 0.05 were taken to be significant.

RESULTS

Confirmatory polynomial regression rejected the differential score model in all three groups. For each condition, exploratory polynomial regression found that linear terms indicated the best fitting model for predicting adherence. In all groups, adherence increased as necessity beliefs increased and concerns decreased. Patients suffering from cardiovascular conditions and diabetes with low necessity and low concerns beliefs reported higher medication adherence compared to those with high necessity and high concerns beliefs.

DISCUSSION

Alleviating patients' concerns can enhance medication adherence and potentially curb the issue of medication wastage.

摘要

目的

“必要性-担忧框架”是一个重要的框架,可帮助医疗保健专业人员针对患者的药物信念和用药依从性决策。我们的目的是确定在三种慢性疾病中,药物依从性的“必要性”和“担忧”信念的相互依存性如何比较。

方法

在门诊诊所就诊的哮喘、心血管疾病或糖尿病患者完成了一份自我管理问卷。该问卷收集了有关人口统计学、用药依从性(使用“用药行为筛查工具”)、家庭中未使用药物以及用药信念(使用“药物信念问卷特定版”)的信息。应用多项式回归来确定对用药依从性的“必要性”和“担忧”信念的多维相互依存性。≤0.05 的值被认为具有统计学意义。

结果

在所有三组中,验证性多项式回归均拒绝了差异评分模型。对于每种情况,探索性多项式回归发现线性项表示预测依从性的最佳拟合模型。在所有组中,随着必要性信念的增加和担忧的减少,依从性增加。与高必要性和高担忧信念的患者相比,低必要性和低担忧信念的心血管疾病和糖尿病患者报告的药物依从性更高。

讨论

减轻患者的担忧可以提高药物依从性,并可能遏制药物浪费问题。

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