Puette Jeffrey A., Malek Ryan, Ahmed Intisar, Ellison Matthew B.
West Virginia University
Mclaren Macomb
Pacemakers are adjustable artificial electrical pulse generators, frequently emitting a pulse with a duration between 0.5 and 25 ms with an output of 0.1 to 15 V at a frequency of up to 300/min. The cardiologist or pacemaker technologist will be able to interrogate and control the pacing rate, the pulse width, and the voltage, whether the device is temporary or permanent. Pacemakers are typically categorized as temporary and permanent. Temporarily, pacemakers are almost always placed to stabilize the patient temporarily or facilitate some surgical procedure. The implantable pacemakers are usually permanent and often significantly more complex than temporary pacemakers. The true beginning of the concept of a pacemaker began over 200 years ago. In the late 1700s, Luigi Galvani discovered that he could cause the contraction of a frog's heart simply by passing an electrical current through the heart. This concept was further realized nearly 100 years later with the first successful resuscitation of a child by Guilliame de Boulogne using electricity. He accomplished this by introducing an electrical current to the patient's chest with a return electrode on the leg after a drowning. After this feat, many successful resuscitations were reported, leading to Dr. Hyman's term "artificial cardiac pacemaker" in 1932. Pacemakers are one cardiac implantable electronic device type (CIED). This broad category also includes implantable cardioverter-defibrillators (ICDs). This group of devices was introduced in the 1950s, shortly after the advent of the transistor. As technology has improved, so has the pacemaker device. The first implantable ICD was developed in 1980. Since then, it has become more challenging to differentiate between pacemakers and ICDs because every ICD currently implanted has an antibradycardia pacing function. The patient and any clinician should understand which device has been implanted to prevent unnecessary ICD therapy, which is most likely to occur with any electromagnetic interference and could lead to device activation with an ICD. Most types of CIED use several insulated lead wires with non-insulated tips that are implanted in the heart, either by percutaneous vein insertion or directly by a cardiac surgeon. Cardiac pacemakers comprise the pulse generator and the leads or electrodes. The North American Society of Pacing and Electrophysiology and the British Pacing and Electrophysiology Group jointly developed a generic pacemaker code utilized worldwide that would allow clinicians and manufacturers to describe the device's characteristics, which was last updated in 2002 (see . Pacemaker Table). The first letter in the code indicates which chamber is paced; the second letter indicates which chamber is being sensed by the device; the third letter indicates if there is a response to sensing; the fourth position indicates whether the device will modulate or change the programmed rate independent of the patient's cardiac activity, for example, with exercise; the fifth and last letter of the code indicates additional multisite pacing. The last 2 letters of the code (in the fourth and fifth position) are rarely used in typical nomenclature. The latest generation of pacemakers has many capabilities. The simplest settings are AAI and VVI. The AAI mode paces and senses in the atrium, and each sensed event triggers the generator to fire within the P wave. The VVI mode paces and senses the ventricle and is suppressed by a sensed ventricular event.
起搏器是可调节的人工电脉冲发生器,通常发出持续时间在0.5至25毫秒之间的脉冲,输出电压为0.1至15伏,频率高达300次/分钟。心脏病专家或起搏器技术人员能够询问和控制起搏频率、脉冲宽度和电压,无论该设备是临时性的还是永久性的。起搏器通常分为临时性和永久性两类。临时性起搏器几乎总是用于临时稳定患者病情或便于进行某些外科手术。植入式起搏器通常是永久性的,而且往往比临时性起搏器复杂得多。起搏器概念的真正起源始于200多年前。18世纪后期,路易吉·伽伐尼发现,只需让电流通过青蛙心脏就能使其收缩。近100年后,吉利亚姆·德·布洛涅首次成功用电复苏一名儿童,这一概念得到了进一步实现。他在溺水后通过将电流引入患者胸部并在腿部设置返回电极完成了这一操作。在此壮举之后,许多成功的复苏案例被报道,促使海曼医生在1932年提出了“人工心脏起搏器”这一术语。起搏器是心脏植入式电子设备(CIED)的一种类型。这一广泛类别还包括植入式心脏复律除颤器(ICD)。这类设备在晶体管问世后不久的20世纪50年代被引入。随着技术的进步,起搏器设备也在不断发展。第一台植入式ICD于1980年研发出来。从那时起,区分起搏器和ICD变得更具挑战性,因为目前植入的每一台ICD都具有抗心动过缓起搏功能。患者和任何临床医生都应该了解植入了哪种设备,以防止不必要的ICD治疗,这种情况最有可能在受到任何电磁干扰时发生,并可能导致ICD设备激活。大多数类型的CIED使用几根绝缘导线,其末端为非绝缘的,通过经皮静脉插入或由心脏外科医生直接植入心脏。心脏起搏器由脉冲发生器和导线或电极组成。北美起搏与电生理学会和英国起搏与电生理学会联合制定了一个在全球范围内使用的通用起搏器代码,使临床医生和制造商能够描述设备的特性,该代码最后一次更新是在2002年(见起搏器表格)。代码中的第一个字母表示起搏的腔室;第二个字母表示设备所感知的腔室;第三个字母表示是否对感知有反应;第四个位置表示设备是否会独立于患者的心脏活动(例如在运动时)调节或改变编程频率;代码的第五个也是最后一个字母表示额外的多部位起搏。代码的最后两个字母(第四和第五个位置)在典型的命名法中很少使用。最新一代的起搏器具有许多功能。最简单的设置是AAI和VVI。AAI模式在心房起搏并感知,每次感知到的事件都会触发发生器在P波内放电。VVI模式在心室起搏并感知,会被感知到的心室事件抑制。