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孕早期药物流产后宫腔镜下清除残留妊娠物

Hysteroscopic removal of retained products of conception following first trimester medical abortion.

作者信息

Smorgick Noam, Levinsohn-Tavor Orna, Ben-Ami Ido, Maymon Ron, Pansky Moty, Vaknin Zvi

机构信息

Department of Obstetrics and Gynecology, Assaf Harofeh Medical Center, Affiliated with Tel-Aviv University, Sackler School of Medicine, Israel.

出版信息

Gynecol Minim Invasive Ther. 2017 Oct-Dec;6(4):183-185. doi: 10.1016/j.gmit.2017.05.002. Epub 2017 Jun 13.

Abstract

STUDY OBJECTIVE

To investigate the use of operative hysteroscopy instead of traditional curettage in women with retained products of conception (RPOC) following first trimester medical abortion, with the aim of reducing post-operative intrauterine adhesions.

DESIGN

Retrospective study.

SETTING

Gynecology department in a University affiliated hospital.

PATIENTS

All women treated by hysteroscopy for RPOC following first trimester medical abortion using the mifepristone-misoprostol protocol for pregnancy termination or the misoprostol protocol for early missed abortion from January 2013 to August 2016.

INTERVENTION

Operative hysteroscopy for removal of RPOC. Post-operative intrauterine adhesions were assessed by diagnostic office hysteroscopy after 6-8 weeks.

MEASUREMENTS AND MAIN RESULTS

50 cases were identified. The mean time from medication administration to the operative hysteroscopy was 1.7 ± 0.7 months. Operative hysteroscopy with blunt use of the resectoscopic loop was used to remove all specimens, and all procedures were completed without intra-operative complications. Two patients (4.0%) were readmitted for fever. Pathology confirmed the presence of RPOC in 45 (90.0%) cases. On follow-up office hysteroscopy, a normal uterine cavity without evidence of intrauterine adhesions was seen in 29/29 (100%) women.

CONCLUSION

Hysteroscopy for removal of RPOC following medical abortion is associated with low rates of complications and post-operative intrauterine adhesions.

摘要

研究目的

探讨在孕早期药物流产后妊娠物残留(RPOC)的女性中使用宫腔镜手术替代传统刮宫术,以减少术后宫腔粘连。

设计

回顾性研究。

地点

一所大学附属医院的妇科。

患者

2013年1月至2016年8月期间,所有因RPOC接受宫腔镜治疗的女性,这些女性在孕早期药物流产时采用米非司酮 - 米索前列醇方案终止妊娠或采用米索前列醇方案治疗早期稽留流产。

干预措施

采用宫腔镜手术清除RPOC。术后6 - 8周通过诊断性宫腔镜检查评估宫腔粘连情况。

测量指标及主要结果

共纳入50例患者。从用药到进行宫腔镜手术的平均时间为1.7±0.7个月。使用钝性的宫腔镜切除环进行手术以清除所有标本,所有手术均无术中并发症。2例患者(4.0%)因发热再次入院。病理检查证实45例(90.0%)存在RPOC。在随访的宫腔镜检查中,29/29例(100%)女性子宫腔正常,无宫腔粘连迹象。

结论

药物流产后采用宫腔镜清除RPOC的并发症发生率及术后宫腔粘连发生率较低。

https://cdn.ncbi.nlm.nih.gov/pmc/blobs/3035/6135206/4adc5ccd07f4/GMIT-6-183-g001.jpg

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