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舒张功能障碍:透析中被低估的新挑战

Diastolic Dysfunction, an Underestimated New Challenge in Dialysis.

作者信息

Escoli Rachele, Carvalho Maria J, Cabrita António, Rodrigues Anabela

机构信息

Department of Nephrology, Centro Hospitalar do Médio Tejo, Torres Novas, Portugal.

Department of Nephrology, Hospital de Santo António, Porto, Portugal.

出版信息

Ther Apher Dial. 2019 Apr;23(2):108-117. doi: 10.1111/1744-9987.12756. Epub 2018 Sep 25.

Abstract

Heart failure (HF) is very common in the general population and specifically in CKD patients due to higher prevalence of traditional and CKD-related risk factors. In particular, HF with preserved ejection fraction (HFpEF) can affect over 50% of dialysis patients. However, little is known about this entity in CKD. It has been inadequately recognized over time and few data exist regarding clinical profiles and outcomes in dialysis patients. The aim of this paper is to do a critical appraisal of the diagnosis, clinical impact, and management of HFpEF with a focus on new diagnostic criteria and its impact on dialysis.

摘要

心力衰竭(HF)在普通人群中非常常见,尤其是在慢性肾脏病(CKD)患者中,这是由于传统风险因素和与CKD相关的风险因素的患病率较高。特别是,射血分数保留的心力衰竭(HFpEF)可影响超过50%的透析患者。然而,关于CKD中的这一实体知之甚少。随着时间的推移,它一直未得到充分认识,关于透析患者的临床特征和预后的数据也很少。本文的目的是对HFpEF的诊断、临床影响和管理进行批判性评估,重点关注新的诊断标准及其对透析的影响。

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